Prostate Flashcards

1
Q

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Glandular units in the prostate that undergo an incr in the # of cells, resulting in enlargement of the prostate gland

Does not predispose to development of prostate ca

  • the most common urological problem in males
  • as enlarge becomes a problem, it presses against the urethra & leads to obstruction (can be partial or complete)
A

Benign Prostatic Hyperplasia (BPH)

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2
Q
  • Causes a narrowing of the urethra
  • As prostate enlarges, it extends upward into bladder & inwards
A
  • Bladder outlet obstruction is a result of the enlarged prostate
    > urinary sx’s
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3
Q

BPH Cues

  • urinary freq/hesitancy
  • nocturia
  • hematuria
  • reduced force & size of urinary stream
  • straining
  • post-void dribbling
A
  • UTI’s & renal calculi
    > probably d/t incomplete emptying of bladder & urinary stasis
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4
Q

Possible Risk Factors

  • Fhx
  • Obesity (inc waist circumference)
  • Physical activity lvl
  • Alcohol consumption, smoking
  • Diabetes
A
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5
Q

Recognize Cues: Diagnostic Studies

  • HPE
  • DRE
    > is to palpate the prostate
    > BPH feels soft, non-tender, whereas ca feels hard, tender to touch & w/irregular borders
  • Urinalysis w/culture
    > to r/o UTI
A
  • CBC
    > to r/o any infections
  • PSA lvl
    > to r/o prostate ca
    > Normal is 4 or under
  • recent ejaculation or ejaculation within 24-48 hrs can falsely ↑ lvl
  • BUN, creat
    > assess kidney function
  • US
    > can be done abdominally or rectally to look @ the prostate
  • Cystoscopy
    > to look @ the bladder, bladder neck, & urethra. Is inserted through the urethra
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6
Q

Assessment

  • experience any urinary sx’s?
  • ask about urinary pattern, freq, how many times a night gets up
  • any other sx’s of bladder obstruction?
    > r/o either pt has BPH or if UTI or STD

IPSS - International Prostate Symptoms Score
- self-admin tool & pt reviews categories

A

Treatment options algorithm

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7
Q

BPH: Potential Complications

↠ UTI/sepsis
> primarily d/t incomplete emptying of the bladder
> leads to stasis of urine & inc bacterial growth

↠ Renal calculi
> d/t alkalization of the residual urine

↠ Renal failure
> by hydronephrosis

A

↠ Pyelonephritis
> from incomplete emptying of bladder & urinary stasis

↠ Bladder damage
> cumulatively from pt not emptying bladder completely

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8
Q

Non-Surgical Management

Drug Therapy
- depends on sx’s & severity of dz
- shrink the prostate by lowering the DHT, or dihydrotestosterone lvl
- constrict the prostate, reduce urethral pressure, & improve urine flow

A
  • 5-alpha reductase inhibitors
  • Proscar (finasteride)
  • Avodart (dutasteride)
  • alpha-1 selective blocking agents
  • Flomax (tamsulosin)
  • Hydride
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9
Q
  • rx’s can take up to 6 mos to take effect
  • s/e = dizziness, orthostatic hypotension, liver dysfunction
A

CAMs

  • vitamins, herbs (Saw palmetto, lycopene)
    > check for rx interactions
  • avoid caffeine, alcohol
  • maintain an ideal wt
  • inc activity & void as soon as you feel the urge
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10
Q

Thermal therapy

Destroys excess prostate tissue
- water-induced thermotherapy & transurethral ethanol ablation

A

Surgical Procedures

↠ Transurethral Resection of the Prostate (TURP)

↠ Prostatectomy
- Suprapubic
- Retropubic
- Perineal

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11
Q
  • Which proc depends on pt’s gen cond, size of prostate gland, & man’s preference
  • TURP most common
A
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12
Q

?

This is removal of the entire prostate that can be done for those pt’s whose sx’s are very severe

A

Prostatectomy

  • suprapubicly, retropubicly, or perineal
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13
Q

?

A large portion of the prostate is removed endoscopically

  • Requires less anesthesia & lowers rate of complications; epidural or spinal anesthesia
  • Is safer for the high-risk person b/c a surgical incision is not used as opposed to an open incision

> Is no guarantee that the prostate tissue won’t regrow & enlarge >surgery (tissue growth takes yrs so pts may see results for a while)

A

Transurethral Resection of the Prostate (TURP)

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14
Q

CBI (Continuous Bladder Irrigation)

  • 3-way urinary catheter w/a 30-45 mL retention balloon through the urethra into the bladder
  • > a TURP or prostatectomy to irrigate & keep urinary flow clean; to make sure area is healing
  • Traction via taping to pt’s abd or thigh
  • left in place for 24-72 hrs depending on what urine looks like

! There’s going to be bleeding & 1 way to stop the bleeding is to flush the area w/solution

A
  • Uncomfortable urge to void continuously
    > d/t a 30-45 mL retention balloon in place (compared to a Foley cath balloon that’s 10cc)

! Small clots & reddish to pink tinge in the foley bag is expected but fluid should not have large clots or be completely dark red so you can’t see through it

  • Antispasmodic rx’s
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15
Q

Postop Assessment of TURP

  • Monitor for s/s of infection
  • Monitor for confusion
  • Monitor pain
  • OOB asap
  • Monitor color, consistency, & amt of urine output
    > Subtract the amt that’s gone in from the total amt that you get in the drainage bag
  • Monitor for obstruction
A
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16
Q

Prostate Cancer

↠ Most common type of cancer in men
↠ Androgen-dependent adenocarcinoma
↠ Most common place is posterior lobe or outer portion of the prostate gland (whereas BPH is center)

A
  • Slow-growing
  • Metastasizes to lymph nodes, bones, lungs, liver; bones incl pelvis, sacrum, & L/S
17
Q

Risk Factors

  • Age >55 (median age 72)
  • Diet low in fruits & vegetables
  • Fhx
A

Screening

↠ DRE

↠ PSA
> ejaculation & infection will falsely elevate

↠ Biopsy
> done rectally

↠ TRUS (transurethral US)

18
Q

Surgical Management

↠ TURP

↠ Laparoscopic radical prostatectomy

A

↠ Open radical prostatectomy
> to remove not only the prostate but seminal vessels & regional lymph nodes
> the pt will be sterile >a prostatectomy & may or may not have temporary or permanent ED

↠ Bilateral orchiectomy
> removes both testicles; will dec hormone production, slowing rate of ca

19
Q

Complications of Radical Prostatectomy

↠ hemorrhage
↠ urinary retention
↠ infection
↠ wound dehiscence
↠ DVT
↠ PE
↠ ED
↠ Incontinence

A
20
Q

Nonsurgical Management

↠ Radiation
* internal or external
> internal, or brachytherapy, done by inserting radiation seeds into & around the prostate gland; dose is low & not harmful to pt & others
> external beam rad therapy helps treat ca confined to prostate and/or surrounding tissues

↠ Hormones

A

↠ Chemotherapy
> for those whose ca has spread & other therapies haven’t worked

↠ Cryotherapy

↠ CAMs
- foods high in omega 3 fatty acids, lycopene, soy products, green tea

21
Q

Nursing Management

↠ Education
↠ Provide support
↠ Suggest resources
↠ Relieve pain

A
22
Q

Testicular Cancer

> Occurs in men 15-34
Unilateral or bilateral (bilat rare but can happen)
Germ cell vs non-Germ cell tumors
- Germ cell tumors arise from sperm-producing cells (! majority of ca’s)

A
  • non-Germ cell tumors arise from cells that produce testosterone

> Teach self-examination
- has a high success rate; use surgery & chemo

23
Q

Lab Assessment

> Alpha-fetoprotein (AFP)
Beta human chorionic gonadotropin (hcg)
Lactate dehydrogenase (LDH)

  • elevation of 1 or more of these hormones will help determine what type of tumor it is & how to best treat the pt
A

> US, CT, MRI

24
Q

Interventions

  • Surgery (primary treatment)
  • Chemotherapy
  • Radiation
A