Hysterectomy/Reproductive Disorders Flashcards
Uterine Disorders
- Endometriosis
- Leiomyomas, or fibroids
- Cancer
Endometriosis
- Is endometrial tissue that plants itself outside the uterine cavity
- 2 layers - endometrium & myometrium
> Myometrium - muscle layer (myomectomy = removal of muscle layer)
> Endometrium - what sheds monthly during menses
- Most common implantation sites are pelvis, ovaries, & posterior rectal vaginal wall
- Widespread dz
! Major concern is scarring, inflammation, & adhesion (affected organs stick together)
Relevant Cues: Clinical Manifestations
- Pain (peaks right before onset of menstrual flow)
- Infertility (esp if it affects the fallopian tubes or ovaries)
- Dyspareunia
- Menstrual irregularities
- GI disturbances (like nausea, diarrhea, some pelvic tenderness)
Diagnostic
- Health hx, pelvic exam
- Laparoscope
- US (transvaginal; to rule out masses)
Take Action: Treatment
- NSAIDs (i.e., ibuprofen, naproxen)
- OCP’s (i.e., low dose estrogen, progesterone [to shrink endometrial tissue])
- regulate flow
- decrease endometrium
- help w/pain
- Lupron/Synarel
> can medically induce menopause & thereby suppress ovarian function
- Calcium, magnesium supplements
- Relaxation techniques
- yoga, massage, biofeedback
- Heat
- Surgery
- laparoscopically to remove endometrial tissue from areas outside uterine cavity
! decrease the pain; restore sexual or fertility function; alleviate anxiety; educate pts
?
Are uterine tumors that arise from the myometrium
Are benign, slow growing, solid tumors of the uterine myometrium, the muscle layer of the uterus
- 20-30% women
- vary in size; if you have 1, probably have >1
- are probably stimulated by estrogen & progesterone; get bigger during pregnancy & shrink >menopause
- nulligravidas are @ higher risk but unsure why
Leiomyomas, or fibroids
Relevant Cues: Clinical Manifestations
- May be totally asymptomatic or very severe; depends on size of fibroid, location, & how many
- Bleeding
- Anemia
- Dysmenorrhea
- Pelvic pressure/back pain
- Urinary retention/frequency
- Infertility
- Spontaneous abortions, miscarriages
Diagnosis
- Health history; pelvic exam
- U/S (transvag)
- Laparoscopic exam
- CBC (to check for anemia d/t bleeding)
Take Action: Treatment
- Hormone Therapy (HT)
- Laser surgery
- Myomectomy
- Uterine artery embolization
- Hysterectomy
What’s the woman’s desire for future fertility?
! Complications incl perforation, bleeding, & infection
All can be done outpt except for hysterectomy
Which 2 procedures help preserve fertility?
laser surgery; myomectomy
Ovarian Disorders
Cancer
* Leading cause of death from female reproductive cancers
* 5th most common cancer in women
* Sx’s are vague & benign
> Survival rates are very low b/c we don’t detect it until late stage
Cysts
* Usually benign
* Lupron
- Rare >menopause
Ovarian Cancer Risk Factors
↠ Nulliparity
↠ H/o infertility
↠ Family hx
↠ Age (>40)
↠ Fertility rx’s (ovulation-stimulating rx’s)
↠ Use of baby talc
Relevant Cues: Clinical Manifestations
- Persistent GI/GU disturbances (tumor enlarging & causing pressure against GI system & bladder)
- Abd distention w/ascites
- Inc abd girth
- Urinary freq/urgency/pain/pressure
- Malnutrition w/wt loss
- Pain
Take Action: Treatment
↠ Surgery
- remove tumor & ovaries; a hysterectomy may or may not be done
- surgery to dec estrogen
- will be putting the woman into a surgical menopause
↠ Chemotherapy
↠ Radiation
↠ Supportive therapies
Uterine (Endometrial) Cancer
- Endometrial cancer is a reproductive cancer, of which adenocarcinoma is the most common type
> is very curable if caught early; 80% of all cases of uterine ca - The main sx is bleeding:
premenopausal heavy or irregular bleeding
postmenopausal bleeding
- Diagnostic assessment incl
> CA-125 tumor marker
> Cxr
Endometrial Cancer Risk Factors
↠ Early onset of menarche
↠ Late menopause (are exposed to estrogen for a longer period of time)
↠ Obesity
↠ Nulliparity
↠ Reproductive cancers (i.e., if you have had ovarian ca)
↠ Tamoxifen use (for breast ca)
↠ Fhx
↠ DM
↠ HTN
! Common sites for metastasis are liver, lungs, & brain
Endometrial Ca
- Stages 1-4
Stage ___
Cancer has spread beyond the uterus but remains confined to the pelvis, such as in bladder or rectum
3
Stage ___
Tumor is confined to the uterine corpus
1
Stage ___
Highest lvl of invasiveness b/c ca has spread beyond the pelvis, causing metastatic dz & large masses, like in the liver or lungs
4
Stage ___
In addition to the uterine corpus, ca has invaded the cervix
2
Relevant Cues: Clinical Manifestations
- Bleeding (AUB, esp in postmenopausal women)
- Pelvic pressure
- Pain
↠ Dx = endometrial biopsy
Types of Hysterectomies
↠ Total hysterectomy
↠ Partial hysterectomy
↠ Panhysterectomy aka TAH-BSO
↠ BSO
↠ Radical hysterectomy