Propranolol

Question 1

Propranolol (Inderal)

Class

Answer 1

Beta-adrenergic blocker, antiarrhythmic (Class II)

Question 2

Propranolol (Inderal)

Mechanism of Actions

Answer 2

Nonselective beat-adrenergic blocker that inhibits chronotropic, inotropic, and vasodilator response to beta-adrenergic stimulation.

Question 3

Propranolol (Inderal)

Indications

Answer 3

Hypertension, angina pectoris,

Question 4

Propranolol (Inderal)

Contraindications

Answer 4

Sinus bradycardia, second- or third-degree AV block, asthma, CHF, and COPD.

Question 5

Propranolol (Inderal)

Adverse Reactions

Answer 5

Bradycardia, heart blocks, angina pectoris, palpitations, syncope, and bronchospasm.

Question 6

Propranolol (Inderal)

Drug Interactions

Answer 6

Verapamil may worsen AV conduction abnormalities. Succinylcholine effects may be enhanced.

Question 7

Propranolol (Inderal)

Adult Dosage

Answer 7

Dilute 1 – 3 mg in 10 – 30 mL of D5W; administer slowly at a rate of 1 mg/min; maximum 5 mg.

Question 8

Propranolol (Inderal)

Pediatric Dosage

Answer 8

0.01 – 0.05 mg/kg/dose slow IV over 10 minutes; maximum dose 3 mg.

Question 9

Propranolol (Inderal)

Onset

Answer 9

15 – 60 minutes

Question 10

Propranolol (Inderal)

Peak Effect

Answer 10

Variable

Question 11

Propranolol (Inderal)

Duration

Answer 11

6 – 12 hours

Question 12

Propranolol (Inderal)

Special Considerations

Answer 12

Use with caution in the geriatric patient, atropine should be readily available.