Propofol Flashcards
Propofol (Diprovan)
Class
Sedative/hypnotic
Propofol (Diprovan)
Mechanism of Actions
Unclear but appears to inhibit GABA activity in the brain
Propofol (Diprovan)
Indications
Induction or maintenance of sedation
Propofol (Diprovan)
Contraindications
Hypersensitivity to the drug, eggs, or soybean products
Propofol (Diprovan)
Adverse Reactions
Pain, hypotension, apnea, headache, nausea, and vomiting
Propofol (Diprovan)
Drug Interactions
Morphine increases the risk of CNS and cardiorespiratory depression
Propofol (Diprovan)
Adult Dosing
25 – 75 mcg/kg as needed
Propofol (Diprovan)
Pediatric Dosing
1 mg/kg IV
Propofol (Diprovan)
Onset
40 Seconds
Propofol (Diprovan)
Peak Effect
1 minute
Propofol (Diprovan)
Duration
3 - 5 Minutes
Propofol (Diprovan)
Special Considerations
A potent sedative that should only be used with adequate monitoring and resuscitation equipment available.