Demerol

Question 1

Meperidine (Demerol)

Class

Answer 1

Opioid analgesic

Question 2

Meperidine (Demerol)

Mechanism of Action

Answer 2

Synthetic opioid analgesic that acts on opioid receptor sites to produce analgesia, Scheduled narcotic

Question 3

Meperidine (Demerol)

Indications

Answer 3

Analgesia for moderate to severe pain

Question 4

Meperidine (Demerol)

Contraindications

Answer 4

Hypersensitivity to narcotics, diarrhea caused by poisoning, patients taking MAOIs, during labor or delivery of a premature infant, undiagnosed abdominal pain or head injury

Question 5

Meperidine (Demerol)

Adverse Reactions

Answer 5

Respiratory depression, sedation, apnea, circulatory depression, arrhythmias, shock, increased ICP

Question 6

Meperidine (Demerol)

Drug Interactions

Answer 6

Do not give concurrent with MAOIs, exacerbates CNS depression

Question 7

Meperidine (Demerol)

Adult Dosage

Answer 7

50 – 100 mg IM, SC or 25 – 50 mg slow IV

Question 8

Meperidine (Demerol)

Pediatric Dosage

Answer 8

1 – 2 mg/kg/dose IV, IO, IM, SC

Question 9

Meperidine (Demerol)

Onset

Answer 9

IM 10 – 45 minutes, IV immediate

Question 10

Meperidine (Demerol)

Peak Effect

Answer 10

30 – 60 minutes

Question 11

Meperidine (Demerol)

Duration

Answer 11

2 – 4 hours

Question 12

Meperidine (Demerol)

Special Considerations

Answer 12

Naloxone should be readily available