Properties of plasma proteins Flashcards
What is the molecular weight of Albumins?
69,000
Molecular weight of Globulins
90,000-156,000
What is the molecular weight of Fibrinogen?
500,000
Which plasma protein is primarily responsible for regulation of the oncotic plasma?
Albumin
What is the oncotic pressure exerted by the plasma proteins in the capillaries?
About 25mmHg
What is the specific gravity of plasma proteins?
1.026
Electrical neutrality exhibited by plasma proteins is due to
Isoelectric point
Electrophoretic mobility of plasma proteins
Ability of the plasma proteins to act as anions in basic solutions and as cations in acidic solutions.
Can plasma proteins be precipitated by salts?
Yes, they can be precipitates different conc. Of salts.
Solubility of plasma proteins in plasma?
This is achieved by their polar residues in their AA chains…..NH
Ability of plasma proteins to act as buffers in plasma is due to which property?
Amphoteric nature
Where is Albumin synthesized in the Body?
The Liver
What is the plasma level of Albumin in plasma?
4g/dl
3.5-5g/dl
What is the half life of albumin in plasma?
About 14-20days
What are the types of Globulins in plasma?
Alpha-1 globulins
Alpha-2 globulins
Beta-1 globulins
Beta-2 globulins
Gamma globulins
What is the plasma conc. Of Globulins?
2.3g/dl
2-3g/dl
Haptoglobin, ceruloplasma and transferrin are examples of which plasma proteins?
Globulins
Which type of globulin is found in Lipoproteins?
Alpha-2 globulins
Transferrin is made up of which type of globulin?
Beta-2 globulin
MW. of Transferrin is 90,000.
Which globulin type is Haptoglobin?
Alpha-2 globulin
MW. 90,000.
What is the name of the growth promoting protein seen in infants and newborn?
Fetuin
What is the role of ceruloplasmin in circulation and what type of globulin is it?
Helps binds with copper and helps in its transport and storage.
It is an Alpha-2 globulin
Wilson’s disease is associated with deficiency of which plasma protein?
Ceruloplasmin
Gamma globulins are mostly seen in…
Immunoglobulins
