Plasma proteins 2 Flashcards
Which stem cells in embryonic development synthesizes plasma proteins?
Mesenchymal cells
Which plasma protein is produced first during embryonic development?
Albumin
Where is alpha and beta globulins often synthesized?
Liver, spleen and bone marrow.
Where is gamma globulins often synthesized?
B lymphocytes
How does dietary proteins affect the synthesis of plasma proteins?
They play a very essential role in the synthesis of plasma proteins.
N.B. Essential AAs must be present in diet for satisfactory synthesis of plasma proteins
Albumin synthesis is often derived from which protein source?
Dietary proteins of animal
Dietary proteins of plant origin often favors the synthesis of which plasma protein?
Globulin synthesis
Factors affecting the synthesis of Plasma proteins?
- Presence of infection in the body reduces plasma protein synthesis
- Exposure to some antigen stimulates formation of antibodies.
- Inflammatory conditions promote the synthesis of number of proteins.
Acute phase protein synthesis in the liver is promoted by which substance and what activates the substance?
Interleukin-1
Activated by macrophages in the body
Prostaglandins are also known to increase the synthesis of acute phase proteins.
Which plasma protein is low in infants?
Gamma globulins
What physiological changes is observed on plasma proteins during pregnancy(esp. 1and 2nd trimesters)?
Albumin and globulin levels decrease which Fibrinogen level increases.