Properties Of insulin Preparations Flashcards
What are the short-acting insulin preparations?
Aspart®, Glulisine, Lispro*, Regular®, Inhaled human insulin
What are the long-acting insulin preparations?
Degludec, Detemir, Glargine?, NPH
What is an example of a 75/25 insulin combination?
75% protamine lispro, 25% lispro
What is an example of a 70/30 insulin combination?
70% protamine aspart, 30% aspart
What is an example of a 50/50 insulin combination?
50% protamine lispro, 50% lispro
What is an example of a 70/30 NPH insulin combination?
70% NPH, 30% regular
What is the onset time for short-acting insulin preparations Aspart, Glulisine and lispro?
<0.25 hours
What is the duration of action for long-acting insulin preparations DETEMIR?
12-24 hours
What is the peak time for regular insulin?
2-3 hours
What is the effective duration for inhaled human insulin?
3 hours
What is the duration of action for Degludec?
42 hours
What is the peak time for Lispro?
0.5-1.5 hours
Onset of action of HR
0.5 to 1 hour
Onset of action of inhaled Human Insulin
<0.5h
Onset of action of Glargine and NPH
2-4 hours
Onset of action of degludec
1-9 hours
Onset of action of Detemir
1-4 hours
Effective Duration of aspart, glulisine, lispro?
3-5 hours
Effective Duration of HR
4-8 hours
Effective Duration of glargine
20-24 h
Effective Duration of NPH
10-16hours
Peak Action of NPH?
How about degludec, determir and glargine?
4-10h
Others- peakless
Peak of inhaled human insulin?
1-2 hours
Effective duration of 75/25, 50/50, 70/30 (nph/regular)?
10-16 hours
