Propagation Of The Nerve Impulse Flashcards

1
Q

All - or - nothing principle

A

Stating that once an action potential is elicited on a nerve fiber it travels the entire length of the fiber

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2
Q

Antidromic conduction

A

Construction of a nerve impulse in a direction opposite to its normal direction

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3
Q

Nerve/ muscle impulse

A

Transmission of an action potential(depolarization process) along the entire length of a nerve or muscle

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4
Q

Orthodromic conduction

A

Conduction of nerve impulse in the normal direction

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5
Q

Saltatory conduction

A

The jumping of the nerve impulse from one node of rancher to another in the myelinated nerve fiber

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6
Q

When does spread of depolarization along a nerve membrane stop

A

Occasionally when the action potential reaches a points on the membrane at which it does not generate sufficient voltage to stimulate the next area of the membrane the depolarization stops

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7
Q

How does continued Propagation of an impulse through out the nerve fiber occur

A

The ratio of action potential to threshold Excitation must be at all times greater than 1 this greater than 1 requirement is calls the safety factor for Propagation

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8
Q

Safety factor for Propagation

A

The requirement that the ratio of action potential to threshold Excitation must be at all times greater than 1.

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9
Q

Characteristics of nerve trunk

A

Nerve consist of many large net fibers which are myelinated and more small nerve fibers that are unmyelinated. Nerve trunk contain twice as many unmyelinated fingers as myelinated fibers

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10
Q

Structure of myelinated fiber

A

Central core is the axon. Axon is filed with axoplasm viscid intracellular fluid. Surrounding the Axon is a myelin steath deposited by schwann cells. And every 1-3mm among the length of myelin sheath is node of ranvier

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11
Q

Part of the nerve that conducts AP

A

Membrane of the Axon conducts the action potential.

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12
Q

how is myelin sheath deposited by schwann cells

A

Schwann cells envelops the Axon forming multiple layers of schwann cell membrane containing the lipid substance shingomyelin Between 2 successive schwann cells a small uninsulated area where ions could flow into the Axon the area called node of ranvier

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13
Q

Sphingomyelin

A

Lipid sub present in myelin sheath. Excellent electrical insulator that decreases ion flow through the membrane.

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14
Q

How do ions flow into the Axon

A

Between 2 successive schwann cells a small uninsulated area 2-3 micrometers in length where ions could flow into the Axon the area called node of ranvier

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15
Q

Saltatory conduction is valued for 2 reasons

A
  1. Increases the velocity of nerve transmission in myelinated fibers as much as 5to 50 folds
  2. Conserves energy for the Axon because only nodes depolarization leading to less loss of ions therefore requiring little energy expenditure to reestablish Na and K concentration across the membrane after series of nerve impulse
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16
Q

Repolarization occurs with little transfer of ions why

A
  1. Excellent insulation by the myelin sheath

2. Decrease in membrane capacitance

17
Q

Erlanger and Gasser classified nerves based on

A
  1. Diameter
  2. Myelination
  3. Conduction velocity
18
Q

Fiber types

A

A alpha, A beta, A gamma, A delta, B and C

19
Q

Golgi tendon organ(GTO)

A

proprioceptive sensory receptororgan that senses changes in muscle tension. It lies at the origins and insertion of skeletal muscle fibers into thetendonsof skeletal muscle

20
Q

A alpha fiber diameter, Myelination, conduction velocity and type of fiber /receptor supplied

A

16micrometers
Myelinated
100m/sec
Golgi tendon Organs, muscle spindles, extrafusal muscle fibers

21
Q

A beta fiber diameter, Myelination, conduction velocity and type of fiber /receptor supplied

A

8 micrometers
Myelinated
50 m/sec
Muscle spindles, skin mechanoreceptors

22
Q

A gamma fiber diameter, Myelination, conduction velocity and type of fiber /receptor supplied

A

5micro meters
Myelinated
25 m/sec
Intrafusal muscle fibers

23
Q

A delta fiber diameter, Myelination, conduction velocity and type of fiber /receptor supplied

A

4 micrometers
Myelinated but thin
15 m/sec
Skin receptors

24
Q

‌ B fibers fiber diameter, Myelination, conduction velocity and type of fiber /receptor supplied

A

3 micrometers
Myelinated
8 m/sec
Preganglionic autonomic fibers

25
Q

C fibers fiber diameter, Myelination, conduction velocity and type of fiber /receptor supplied

A

1 micrometers
Unmyelinated
1m/sec
Preganglionic autonomic, skin receptors