Prolactinoma Flashcards
1
Q
What is prolactinoma?
A
A prolactinoma is an adenoma (benign tumour) of the pituitary gland. (OHCM)
2
Q
Describe the pathophysiology of hyperprolactinaemia.
A
The tumour pushes on surrounding tissues including the pituitary, causing it to produce excess prolactin. It is a non-functioning tumour. Microprolactinomas (<10mm on MRI) are much more common and often asymptomatic. Macroprolactinomas (>10mm) can grow to any size.
(OHCM)
3
Q
Give 3 symptoms of prolactinoma
A
Menstrual abnormality
Headache
Infertility
(lecture 16/4/18)
4
Q
Give 3 signs of prolactinoma
A
Visual field defect - tunnel vision
Galactorrhoea
Hypogonadism
Rare: CSF leak.
5
Q
Describe the management of prolactinoma.
A
Dopamine agonists eg cabergoline. Same investigations as for other pituitary tumours.
