Prognosis Vs Diagnosis Flashcards
What is a prognosis
A prediction about a likely outcome of a disease
What are the prognostic factors?
Demographic
Disease specific
Co-morbid
What is the natural history of a disease
The progression of a disease in a person over time
How do you express the prognosis
Case fatality rate
Five year survival observed survival rate
Median survival time
Relative survival rate
How do you fine the case fatality rate?
Number of people who die from the disease (divided by) the number of people with the disease
What is a lead time
The time between he early detection of disease and the time of usual clinical diagnosis
Why does lead time bias occur?
Because of the failure to account for the lead time when calculating survival
What is the median survival time?
The time that half the population survives
Stages in natural history
Stage
Susceptibility
Pre clinical clinical recovery disability or death