Processes to do w bones (calcification, remodelling)

Question 1

What is calcification?

Answer 1

Mineral salts and ions are deposited in a framework formed by collagen fibres to crystallise and harden the tissue.

Initiated by osteoblasts.

Question 2

What materials contribute to bone hardness and what allows flexibility in bones?

Answer 2

Hardness: crystallised mineral salts

Flexibility - collagen fibres

Question 3

What is bone remodelling?

Answer 3

The ongoing replacement of old bone tissue with new bone tissue

Question 4

What is bone deposition and bone resorption?

Answer 4

Bone deposition – addition of minerals and collagen fibres by osteoblasts

Bone resorption – removal of minerals and collagen fibres by osteoclasts

Question 5

Osteoprogenitor

Answer 5

Unspecialised cells

Undergo cell division

Develop into osteoblasts

Question 6

Osteoblasts

Answer 6

Bone building cells

Bone deposition/calcification

Forms bone ECM/collagen fibres

Question 7

Osteoclasts

Answer 7

Bone resorption (destruction of old bone ECM)

Question 8

Osteocytes

Answer 8

Mature bone cells, maintain daily metabolism