Problem Solving Videos 23-5-14

Question 1

What are the characteristics of Labrador myopathy?

Answer 1

Starts at 8 weeks - 11 months
Tendon reflexes absent
Stabilises around 1 year of age
Gene test available

Question 2

How is myasthenia gravis diagnosed?

Answer 2

Tensilon test
Autoantibodies
Look for thymoma

Question 3

Which antibiotics are contra-indicated with myasthenia gravis?

Answer 3

Any penicillin as make NMJ worse

Give enrofloxacin

Question 4

What are the characteristics of Equine Motor Neurone Disease?

Answer 4

Oxidative fibre neurogenic atrophy and firbrosis of type I muscle fibres (slow twitch)
As muscle become fibrous it shortens = raised tail head

Question 5

How is Equine Motor Neurone Disease diagnosed?

Answer 5

Sacrocaudalis dorsalis medialis biopsy

Question 6

What are the signs of Equine Motor Neurone Disease?

Answer 6

Generalised weakness
Wastage of postural muscles
Shifting weight, excessive recumbency, walk better than they stand
Limbs tucked under body, elevated tail carriage, lowered head carriage, good appetite

Question 7

What is the treatment for Equine Motor Neurone Disease?

Answer 7

6000 iu Vitamin E orally per day

Access to forage

Question 8

What is the prognosis for Equine Motor Neurone Disease?

Answer 8

40% obvious improvement
40% stabilise but constantly compromised
20% continue to deteriorate

Question 9

What are the signs of genetic polyneuropathy in Leonburgers?

Answer 9

Starts with peripheral nerves and slowly moves centrally as disease progresses

Question 10

What are the characteristics of Stringhalt?

Answer 10

Caused by false dandelion intoxification
Distal axonopathy
Recovery possible after removal from pasture