Problem 1: Suboptimal COPD management Flashcards

1
Q

How is COPD diagnosed?

A

Characterised by airflow limitation that is NOT fully reversible. Spirometry tests are needed to confirm diagnosis once clinical signs/symptoms have been considered. Chest x-ray and blood tests needed to rule out differential diagnosis.

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2
Q

What are the key differences in the signs and symptoms of asthma v COPD?

A

Breathlessness in asthma is transient / exercise induced, chronic breathlessness is COPD. Smoking / 35 years and over COPD, younger patients asthma. Chronic productive cough is key sign of COPD. Night time wheezing asthma. Varying symptoms day to day more common in asthmatic patients.

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3
Q

What is the NICE guidance for COPD 2010? Treatment table

A

Draw - FEV1 < 50% and > 50%.

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4
Q

What are the subtypes of COPD?

A

Emphysema (pink puffers)
- good respiratory drive, severe onset of dyspnoea, breathless and pursed lip breathing. Thin, well perfused so pink in colouration.
Chronic bronchitis (blue bloaters)
- minimal breathlessness but respiratory failure (hypoxia and hypercapnia). Overweight, central cyanosis (blue tinge), productive cough, increased purulent sputum.

Polycythemia and Cor Pulmonale are complication associated with chronic bronchitis.

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5
Q

How are the subtypes of COPD managed pharmacologically?

A

Mucus production in blue bloaters with acetylcysteine or carbocysteine.

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6
Q

What is spirometry?

A

Tests lung function; measures the volume of air that can be expelled from a patients lungs (in one second FEV1) and FVC.

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7
Q

What is FEV1 and FVC?

A

Forced expiratory volume in 1 sec

Forced volume capacity

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8
Q

How are spirometry test results obtained? Why are they useful?

A

Obtained from a spirometry machine available in most GP surgeries / hospitals. Handheld device that takes measurements of factors such as FVC and FEV1. Results can be compared to predicted results for age group / patient profile which allows from comparison. Percentages of predicted outcomes and ratios between FVC and FEV1 allow for analysis of a patients lung function.

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9
Q

How to calculate FEV1:FVC and interpret results?

A

FEV1:FVC ratio; interpretation of the results allows for indicators of COPD if ratio is reduced. Also allows to grade the severity of COPD.

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10
Q

How can FEV1 be predicted as a percentage and what does this show?

A

FEV1 predicted values can be found online / BNF p 214

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11
Q

What advice is normally given to patients about inhaler technique for Clenil and salbutamol?

A

See PiL

https: //www.medicines.org.uk/emc/medicine/3860
https: //www.medicines.org.uk/emc/product/6975

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12
Q

What are common problems encountered by patients using these inhalers?

A

Poor inadequate inhaler use technique, oral candiasis as a result of ICS, dry mouth if anti-muscarinic. Poor adherence

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13
Q

What are the options if inhaler technique does not prove effective?

A

Spacer, aerochamber

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14
Q

What evidence based benefits of quitting smoking can you provide to a patient?

A

Cardiovascular: coronary heart disease, angina, stroke, heart attack
Cancers: oesophageal/lung but also elsewhere in the body
Respiratory: lung function, COPD and lung cancer

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15
Q

What effect would smoking cessation impact on the breathing and glaucoma?

A

Slow down progression of COPD, help lungs to function at maximum capacity for as long as possible.
General blood capillaries in the body / cardiovascular health will be improved by smoking cessation. Nicotine vasoconstrictor, smoke damage to eyes, maccular degenration / cataracts also related to smoking.

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16
Q

What are smoking cessation options?

A

Nicotine Replacement Therapy

Varenicline (Champix) partial agonist of nicotinic receptors

17
Q

What NRT products are available for therapy?

A

Patches, gum, lozenges, inhalator

18
Q

How are NRT doses titrated?

A

Nicotine monograph in BNF explains titration

19
Q

How is smoking cessation monitored / followed up?

A

Exhaled carbon monoxide levels measurements

Cotinine (sputum, urine, saliva) can be detected

20
Q

What are the seven stages of smoking cessation?

A

Pre-contemplation
Contemplation: not ready to quit but sees problems associated with smoking
Preparation: you want to quit and prepare to quit
Action
Maintenance
Termination

Relapse

21
Q

What advice would you give to patients about E-cigarettes?

A

Government stance: 95% safer than smoking tobacco and can help patients to quit
GPhC: selling e-cigs is fine so long as up to date and professional judgment information is given to public
RPS: E-cigs not licensed as medicinal products should have advertising and sales restricted.

22
Q

What is pack year history? How is it calculated and how is it valuable?

A

(No. of cig smoked per day x No. of years smoked) / 20

Gives an estimation of how many cigs over a year the person smokes

23
Q

How can patients monitor their own COPD?

A

Symptoms and airflow regularly monitored

Look out for signs and symptoms of infection / exacerbations