prions

Question 1

proteinaceous infectious particles with NO detectable nucleic acid (neither DNA nor RNA).

Answer 1

prions

Question 2

Has the ability to fold into a precise 3-dimensional shape

Answer 2

prions

Question 3

normal form of the protein is called

Answer 3

PrPC

Question 4

infectious form is called

Answer 4

PrPSc

Question 5

“C” refers to

Answer 5

cellular PrP

Question 6

“Sc” refers to

Answer 6

Scrapie-prion disease occuring in sheep

Question 7

are transmissible neurodegenerative conditions that affect the brain and neural tissue of animals and people. It is usually untreatable and fatal.

Answer 7

Prion

Question 8

PROPERTIES OF PRIONS
o Mutation - different folding properties (usually with 3-d conformation)
o Mutated proteins are resistant to proteases
o Resists Heat, UV light, nucleases and formaldehyde
o Inactivated by chemicals that denature proteins. t/f

Answer 8

t

Question 9

Spread of the disease is via ______, i.e., transmission from one person to another, either directly or by fomites or by ingestion of contaminated meat

Answer 9

horizontal transmission

Question 10

Small infectious agents causing plant diseases

Answer 10

viroid

Question 11

Compose of nucleic acid molecules, naked RNA without protein coat

Answer 11

viroid