Principles of Radiation Use, Protection, and Basic Physics Concepts Flashcards

1
Q

What is the MATRIX trial?

A

A large-scale randomized controlled trial comparing radial and femoral access in 8,404 ACS patients

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2
Q

What was the risk ratio for all-cause mortality favoring radial access found in the meta-analysis following the MATRIX trial?

A

0.72 (95% CI 0.60 to 0.88; p = 0.0011)

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3
Q

What is the purpose of digital subtraction angiography?

A

To subtract a non–contrast-filled (mask) image from a contrast-filled (live) image

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4
Q

True or False: Subtraction studies require a lower dose of radiation compared to cardiac cine frames.

A

False

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5
Q

What are the main sources of radiation exposure during interventional procedures?

A

Scatter radiation and primary beam exposure

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6
Q

What is the FDA limit for maximum exposure rate for diagnostic fluoroscopy?

A

88 mGy per minute (10 R per minute)

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7
Q

What is quantum mottle?

A

The background granularity of the image due to random variation in x-ray photon distribution

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8
Q

Fill in the blank: An increase in filament current (mA) _______ the number of x-ray photons produced.

A

increases

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9
Q

How does collimation affect radiation exposure?

A

Reduces exposure for everyone in the room

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10
Q

What is photoelectric absorption?

A

A sudden jump in absorption when incident photon energy exceeds the binding energy of an electron

It is a significant source of tissue attenuation in the diagnostic range.

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11
Q

What are the two categories of radiation exposure-associated risks?

A

Stochastic and deterministic (tissue reactions)

-Stochastic risks are associated with cancer risk
-deterministic risks involve tissue reactions

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12
Q

True or False: Most x-ray-induced DNA damage results from direct structure alteration.

A

False

About two-thirds of cases result from free radical formation (indirect damage).

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13
Q

What does DAP stand for in radiation exposure metrics?

A

Dose Area Product

It is the product of air KERMA and the beam cross-sectional area.

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14
Q

What is the typical effective dose (ED) for a coronary angiography?

A

7 mSv

This exposure is significant compared to other diagnostic procedures.

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15
Q

What does DAP stand for in radiology?

A

Dose Area Product

DAP is also known as kerma-area product and is the product of the air KERMA and the beam cross-sectional area.

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16
Q

How does collimation affect radiation exposure?

A

Reduces beam area, DAP, total patient dose, and room exposure

Collimation is a technique used to limit the size of the x-ray beam.

17
Q

What is the average radiation exposure from standard diagnostic coronary angiography?

A

About 7 mSv

This exposure is equivalent to 2 to 4 years of natural background exposure.

18
Q

What is the radiation exposure from a single-isotope SPECT?

A

10 mSv on average

This is equivalent to 10 years of natural background exposure.

19
Q

True or False: Pregnancy is an absolute contraindication to cardiac catheterization procedures.

A

False

Pregnancy is not an absolute contraindication, but risks must be discussed.

20
Q

What is the guiding principle for radiation safety in medical settings?

A

ALARA (As Low as Reasonably Achievable)

This principle aims to minimize radiation exposure.

21
Q

What is the difference between stochastic and deterministic effects of radiation?

A

Stochastic effects are random and can lead to cancer; deterministic effects have a threshold dose and cause immediate cell death

Stochastic effects are unpredictable, while deterministic effects are predictable and preventable.

22
Q

What are the key technical determinants of x-ray exposure?

A

Table height and detector position

These factors are under the operator’s control and can significantly affect patient dose.

23
Q

The term ‘attenuation’ in radiology refers to what?

A

The reduction of the intensity of x-ray photons as they pass through tissue

Attenuation is influenced by multiple factors including tissue density and thickness.

24
Q

What is the maximum voltage applied to an x-ray tube indicative of?

A

The maximum energy of the x-ray photons spectrum produced

For example, a 70 kVp produces x-rays with energies up to 70 keV.

25
Q

What is recommended when exposing a pregnant woman to radiation?

A

Discuss cancer risk and utilize the smallest amount of radiation needed

Use the ALARA principle and limit the beam to the chest whenever possible.

26
Q

What is the purpose of wearing two dosimeters in a medical setting?

A

To record accumulated doses of scatter radiation effectively

Ideally, one badge should be worn over the thyroid collar and one under the apron.

27
Q

Fill in the blank: The Roentgen unit has been replaced by the _______.

A

Sievert

The Sievert is a measure of the biological effect of radiation on the whole body.

28
Q

What is the significance of the K-edge absorption peak at 33.2 keV?

A

It relates to the transparency of iodine to high-energy photons

This transparency can lead to decreased image contrast in radiological images.

29
Q

What is a common reason for the increased skin entry doses during cardiac fluoroscopy?

A

Patient obesity

Obesity can lead to higher doses due to increased tissue thickness.

30
Q

What does the term ‘effective dose’ refer to in relation to radiation exposure?

A

A measure of the risk of cancer from radiation exposure

This risk is cumulative and varies based on patient age and exposure type.

31
Q

What percentage of medical radiation exposure is attributable to cardiovascular imaging?

A

About 40%

This includes 10% directly attributable to interventional cardiology.

32
Q

What is the purpose of Diagnostic Reference Levels (DRLs)?

A

To control radiation exposure on a population level

DRLs are typically set to the 75th percentile of dose distribution for a specific center.

33
Q

True or False: All radiation exposure potentially adds to the lifetime risk of developing a malignancy.

A

True

This cumulative risk is particularly concerning for younger patients.