Principles of Radiation Use, Protection, and Basic Physics Concepts Flashcards
What is the MATRIX trial?
A large-scale randomized controlled trial comparing radial and femoral access in 8,404 ACS patients
What was the risk ratio for all-cause mortality favoring radial access found in the meta-analysis following the MATRIX trial?
0.72 (95% CI 0.60 to 0.88; p = 0.0011)
What is the purpose of digital subtraction angiography?
To subtract a non–contrast-filled (mask) image from a contrast-filled (live) image
True or False: Subtraction studies require a lower dose of radiation compared to cardiac cine frames.
False
What are the main sources of radiation exposure during interventional procedures?
Scatter radiation and primary beam exposure
What is the FDA limit for maximum exposure rate for diagnostic fluoroscopy?
88 mGy per minute (10 R per minute)
What is quantum mottle?
The background granularity of the image due to random variation in x-ray photon distribution
Fill in the blank: An increase in filament current (mA) _______ the number of x-ray photons produced.
increases
How does collimation affect radiation exposure?
Reduces exposure for everyone in the room
What is photoelectric absorption?
A sudden jump in absorption when incident photon energy exceeds the binding energy of an electron
It is a significant source of tissue attenuation in the diagnostic range.
What are the two categories of radiation exposure-associated risks?
Stochastic and deterministic (tissue reactions)
-Stochastic risks are associated with cancer risk
-deterministic risks involve tissue reactions
True or False: Most x-ray-induced DNA damage results from direct structure alteration.
False
About two-thirds of cases result from free radical formation (indirect damage).
What does DAP stand for in radiation exposure metrics?
Dose Area Product
It is the product of air KERMA and the beam cross-sectional area.
What is the typical effective dose (ED) for a coronary angiography?
7 mSv
This exposure is significant compared to other diagnostic procedures.
What does DAP stand for in radiology?
Dose Area Product
DAP is also known as kerma-area product and is the product of the air KERMA and the beam cross-sectional area.