Principles of Antimicrobials

Question 1

The “-cillin” drugs (Penicillin, amoxicillin, Ticarcillin, ampicillin) are Penicillins that fall under what class of drugs?

Answer 1

Beta-lactams

Question 2

What is the beta-lactam MOA?

Answer 2

cell wall inhibitors

Question 3

Cephalexin, Cefazolin, Ceftiofur, and Cefovecin are what types of drugs? What class do they fall under?

Answer 3

Cephalosporins

Beta-lactams

Question 4

MOA of glycopeptides?

Answer 4

cell wall inhibitors

Question 5

Name a glycopeptide?

Answer 5

Vancomycin

Question 6

Aminoglycoside MOA?

Answer 6

Ribosomal inhibitors (BOTH subunits)

Question 7

Name the two aminoglycosides

Answer 7

Getamycin

Amikacin

Question 8

Name the 4 categories of “static” ribosomal inhibitors

Answer 8

tetracyclines
phenicols
lincosamides
macrolides

Question 9

Name the lincosamides

Answer 9

clindamycin

Question 10

Name the macrolides

Answer 10

Tilmicosin

Azithromycin

Question 11

The fluororuinolones have what common ending?

Answer 11

“-floxacin”

Question 12

Metronidazole and Rifampin are what class of drug?

Answer 12

Fluoroquinolones

Question 13

Which group of drugs are folic acid inhibitors?

Answer 13

sulfonamides

Question 14

Name the sulfonamides

Answer 14

Sulfadiazine

Trimethoprim

Question 15

A drug that acts irreversibly with its target receptor is most likely to be time or concentration dependent?

Answer 15

concentration

Question 16

A drug that acts reversibly (competitively inhibits) its target receptor is most likely to be time or concentration dependent?

Answer 16

time-dependent

Question 17

Classes of time dependent drugs

Answer 17

Beta-lactams, macrolides, tetracyclines, phenicols, sulfonamides

Question 18

Classes of concentration-dependent drugs

Answer 18

Fluoroquinolones, aminoglycosides