Primary Hemostasis

Question 1

Complex process that stops bleeding and maintains blood in the fluid state

Answer 1

hemostasis

Question 2

Systems involved in maintaining hemostasis: BPCFS

Answer 2

blood vessels
platelets
coagulation factors
fibrinolysis
serine protease inhibitors

Question 3

response to vascular injury; formation of platelet plug/white clot

Answer 3

primary hemostasis

Question 4

activation of coagulation proteins to produce fibrin

Answer 4

secondary hemostasis

Question 5

Prostacyclin; nitric oxide; endothelin

Answer 5

platelet inhibitor; vasodilator; vasoconstrictor

Question 6

Reduced if injury to the endothelial cells occur promoting vasoconstriction

Answer 6

prostacyclin and nitric oxide

Question 7

vasoconstriction is promoted by

Answer 7

epinephrine and serotonin

Question 8

Happens due to reduced prostacyclin (platelet inhibitor)

Answer 8

platelet adhesion

Question 9

attaches to the GP Ib resulting to platelet adhesion

Answer 9

vWF

Question 10

the shape change of platelet due to contraction of the microtubules

Answer 10

disk shape to spherical

Question 11

Platelet stimulating agents that cause platelets to adhere with each other

Answer 11

atp
collagen
epinephrine
thrombin

Question 12

act as a cofactor by binding with GP IIb/IIIa in platelets.

Answer 12

fibrinogen

Question 13

binding of GP IIb/IIIa by fibrinogen is stimulated by presence of

Answer 13

Ca2+ and Mg2+

Question 14

also causes platelet aggregation

Answer 14

prostaglandins

Question 15

hydrolize phospholipids to release arachidonic acid

Answer 15

phospholipases

Question 16

metabolize arachidonic acid to form final product

Answer 16

cyclo-oxygenase

Question 17

a vasoconstrictor, platelet activator, causing platelet secretion and aggregation

Answer 17

thromboxane A2

Question 18

Irreversible step

Answer 18

aggregation

Question 19

reversible step

Answer 19

adhesion

Question 20

All test tubes used for coagulation studies should have ________ surface such as glass.

Answer 20

noncontact

Question 21

ratio of blood to anticoagulant

Answer 21

9:1

Question 22

ratio of anticoagulant to blood

Answer 22

1:9

Question 23

specimen should be centrifuged with

Answer 23

1 hour

Question 24

complete testing should be done

Answer 24

within 2 to 4 hours

Question 25

indicative of a traumatic venipuncture

Answer 25

hemolyzed sample