Prevent Onset UHR

Question 1

Prevent onset intro

Answer 1

UHR- focusing on people who may be at increased risk of developing psychosis/ or other psychotic disorders
A number of different interventions have been used to prevent development
- commonly tested interventions in this field are CBT
However evidence base of this intervention is not clear
A recent meta analysis is a good example of this

Question 2

Prevent onset- Davies et al (2015)

Answer 2

Davies et Al (2015) data from 14 studies in a MA
compared how well a series of interventions prevented onset - 2 forms of CBT, integrated psychological intervention, family therapy, antipsychotic and a needs based intervention (active control)
At 6 month follow up- antipsychotic plus needs based intervention were most effective
At 12- no interventions were more effective than the needs based
More recent novel intervention may be effective

Question 3

Prevent onset- pozza and dettore (2020)

Answer 3

Novel new intervention tested
Pozza and dettore(2020)
Found a new intervention that addressed both psychotic symptoms and mood problems which may be effective In the prevention of psychosis
- CBT for psychosis combined with CBT for anxiety and depression
29 received and 29 received control (supportive counselling)
By follow up of 14 months 12% converted to psychosis with control group at 34% - showing a significant different.
Some weaknesses in the study such as small sample size making us question the effectiveness

Question 4

Prevent onset- Pellica et al (2023)

Answer 4

Important to look at real world care setting
An updated longitudinal evaluation on negative symptoms of UHR
(Pellica et Al, 2023)
2 year follow up- 100 individuals aged 12-15 completed questionnaires on negative and positive symptoms after the follow up- sig decrease in negative symptom clinical severity
Found individual psychotherapy may reduce NS
However real world for UHR is scarce and inconclusive