Preterm, prenatal exposures, FASD Flashcards
second hand smoke in 18 months (urine cotinine)
what developmental area affected
may reduce gross motor, fine motor and language development (Wei et al 2021)
Name the FASD treatment categories
4 different treatment domains
2 neuroimaging findings in child with CMV
peri-ventricular or ventricular calcifications
brain atrophy
ventriculomegaly
structural anomali
Congenital Zika features - 3 clinical or imaging findings
Cerebral atrophy, hypoplasia or calcification
Microcephaly
Marked spasticity and hypertonia
club foot or arthrogryposis
Chorioretinal atrophy
2 anatomical aspects of a childs anatomy that make them more susceptible to brain injury
relative macrocephaly
weak neck muscles
Elastic blood vessels
Incomplete myelination
3 sentinal facial features of FASD
6 difficulties in FASD to advise a teacher
Attention
Memory
Executive function
Communication challenges
Emotional dysregulation
Social challenges
Adaptive skills
3 syndrome that have dysmorphic features similar to FAS
22q11 microdeletion
Williams
Noonan
Cornelia de Lange syndrome
Fetal PKU
fetal VPA
Classroom strategies for FASD
Name 5 specific strategies
Area of relative strengths from CANFASD
Auditory memory
Non-verbal abilities
Friendly
Determined and hard working
10 neurodevelopmental domains of FASD
Attention
Executive functioning
Memory
Language
Motor
Social/Adaptive
Academic performance
Cognitive
Affect regulation
Neuroanatomy/Neurophysiology
CLEAN A,S MAMA
What 6 neuropsyc domains with psych and associated tests in FASD
Intellectual Disability - WISC-V or WPPSI IV
Motor Impairment - Beery VMI or BOT 2
Attention impairment - BASC -3 or impairments in processing speed and working memory on WISC, Conners, SNAP-IV
EF impairment - BRIEF2
Language impairment - core language - CELF P3/CELF-5; CELF metalinguistics
Adaptive impairments - ABAS-3 or Vineland 3
Academic impairment - WIAT III or KTEA-3a
3 major signs of FASD
facial features
prenatal alcohol exposure
functional impairments in at least 3 brain based domains
3 diagnosis (DSM) that late term infant is more at risk for (37 weeks)
ADHD
DCD
Specific learning disorder
4 risk factors in neonatal period for school difficulties in ex-preterm
LBW
extreme preterm
HIE
IVH
hypoglycemia
neonatal infection
ROP
name 5 team members for an ex-preterm wtih CP
Neuromotor team
Neurology
Orthopedics
Ophthalmology
Audiologist
Occupational therapy
Physiotherapy
Paediatrician
Social worker
follow up topics in ex 26 weeker to review before starting school
1 test to order in wrestles leg syndrome
ferritin
6 neonatal effects of SSRI in utero
Poor muscle tone
Tremors/jitteriness
Irritability
Seizures
Feeding difficulties
Sleep disturbances
Hypoglycemia
Respiratory distress
PNAS, also referred to as neonatal withdrawal syndrome and serotonin discontinuation syndrome, has been described in up to 30% of newborns exposed to maternal SSRI or SNRI use in utero, particularly during the third trimester
NOT at risk for higher internalizing or anxious behaviors, ADHD or ASD
Maternal mood including depressed mood accounts for most of the child behavioral outcomes.
Agenesis of the corpus callosum
3 developmental/behavioral findings
Impaired attention (ADHD)
ID - delayed cognitive processing
SLD
Impaired pragmatic language skills
Impaired core language
Impaired hand eye coordination
Vision problems
Highly highly variable
Paper (2023) John Willie and Sons
school difficulty that suggest brain abnormality (?absent corpus callosum)
Attention /ADHD
specific learning in math
language
cognition
Name the 9 areas of impairment outside of neuroanatomy/neurophsyiology evaluated in FASD
name 5 clinical features of FASD outside of domains, PAE, and sentinal facial features
Microcephaly
Oral facial cleft
Clinodactyly
Short 5th digits
CHD (ASD, VSD, ToF, great vessel anomalies)
Kidney anomalies
Radioulnar synostosis
Ear malformations
Single palmar crease
Growth restriction
Physical features and imaging findings of Zika (5)
Microcephaly
Ventriculomegaly
Parenchymal or cerebellar calcifications
Atrophic cerebral cortex, cerebellum, brainstem
Corpus callosum anomaly
Hydrocephalus.
Cardiomegaly
Diaphragmatic paralysis (seen on CXR)
