Pressure and flow in arteries and veins Flashcards
systolic pressure
start of tapping sounds
diastolic pressure
silence after thumping sounds
pulse pressure
normal is 120/80 systolic over diastolic
changes in aortic pressure wave as it passes through vascular tree
affected by stroke volume, velocity of ejection, elasticity of arteries, total peripheral resistance
changes in blood velocity and total cross sectional area of the arteries
pressure falls throughout. velocity is related to total cross section- fastest in aorta and vena cava, slowest in capillaries. small drop through arteries, large drop through arterioles, low when gets to capillaries, leaves a small pressure difference pushing blood back through the veins, pulmonary circulation pressure.
things that affect venous pressure and return
gravity, rhythmic skeletal muscle contraction, respiratory pump increases venous return, venomotor tone, systemic filling pressure. this is important because venous return affects end diastolic volume which affects preload which affects the pumping ability of the heart
veins are thin walled so
pressure is low, external influences affect flow
mechanisms that prevent clotting
physical barrier that stops blood contacting collagen, produces prostacyclin and NO which inhibit platelet aggregation, produce tissue factor pathway inhibitor which stops thrombin production, expresses thrombomodulin and heparin which inactivate thrombin, secretes tissue plasminogen activator (t-PA) which breakdown clot
clotting involves
platelet plug, fibrin clot