Presenting Signs: Cough and Dyspnoea Flashcards

1
Q
  1. Define cough.
  2. Define Dyspnoea.
A
  1. Sudden expiratory effort against a closed glottis, results in noisy expulsion of air from lungs.
  2. Difficulty breathing w/ increased effort.
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2
Q
  1. Tachypnoea.
  2. Hyperpnoea.
  3. Orthopnoea.
  4. Cyanosis.
A
  1. Increased RR.
  2. Increased respiratory effort (deeper breaths) w/o dyspnoea.
  3. Difficulty breathing in while laying down. Cats often sit or stand to facilitate breathing w/ elbows abducted and neck extended.
  4. Blue MM colouration due to reduced oxygenation.
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3
Q
  1. Aim of cough.
  2. Cough receptors.
  3. Cough arc reflex.
  4. How does heart disease result in cough?
A
  1. Aim is protective reflex to clear excess secretions / foreign materials.
  2. Cough receptors in large airways and low density cough receptors in nose, sinuses, pharynx, pleura.
    - mechanical receptors for mucus, FB etc.
    - chemical receptors for acid, heat etc.
  3. Cough arc reflex:
    - afferent pathway: sensory nerves (vagus).
    - cough centre: medulla oblongata.
    - efferent pathway: via vagus, phrenic and spinal motor nerves to diaphragm, abdominal wall and muscles.
  4. Enlarged LA.
    Tachypnoea caused by pulmonary oedema.
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4
Q

Harmful effects of coughing.

A

Exacerbate airway inflammation and irritation.
Emphysema.
Pneumothorax.
Weakness and exhaustion.
Dissemination of infections.

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5
Q

Causes of dyspnoea and tachypnoea.

A

Respiratory:
- obstructive – fixed or dynamic obstruction.
- restrictive – decreased volume of air that the lungs can hold.
Cardiac.
Haematologic.
Metabolic.
Neurological.

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6
Q

Approach to the patient presenting w/ dyspnoea and cough.

A

Assess patient:
- O2.
- Reduce stress – consider sedation and environment.
Hx.
PE.
Problem list and differentials.
Dx investigations.
Interventions/management.

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7
Q

Considering the causes of the cough.

A

Cardiac or respiratory?
- what causes coughing in heart disease?
- any other signs of heart disease?
- any other signs of cardiac failure (i.e. dyspnoea and/or tachypnoea)?
– murmur?
- sinus arrhythmia?
– Y –> CHF v unlikely.
– N –> does not help.
- cats w/ heart disease rarely cough.

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8
Q
  1. Likely cause of dyspnoea and cough in young patients?
  2. Likely cause of dyspnoea and cough in older patients?
  3. Breed dispositions for diseases causes coughing and dyspnoea.
A
  1. Lungworm?
  2. Neoplasia? Chronic bronchitis?
  3. Brachycephalic or dolichocephalic.
    Working/outdoor lifestyle - airway FB?
    CKCS and others = MMVD.
    Brachycephalic breeds - BOAS.
    Toy breed dogs e.g. Yorkie - tracheal collapse.
    Siamese cat - Feline asthma/chronic bronchitis.
    Westie - idiopathic pulmonary fibrosis.
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9
Q

Taking a general history.

A

Vac status, contact w/ other animals.
Worming history (lungworm).
History of trauma.
Exercise tolerance.
Environmental influences: rural/urban/tobacco smoke.
Additional clinical signs: - vomiting or regurgitation?

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10
Q

Characterising the clinical signs.

A

Coughing vs panting.
Reverse sneezing, gagging, retching.
Onset and duration:
- acute versus chronic >2mths.
- progressive?
The cough:
- initiating factors.
- Productive vs non-productive.
- sound: moist, gurgling, dry, goose honk.
- Presence of terminal retch.
Change in sound of bark/purr/meow.

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11
Q
  1. Is a patient suffering from BOAS suffering from an obstructive dyspnoea or restrictive dyspnoea?
  2. Is a patient suffering from BOAS suffering from expiratory dyspnoea, inspiratory dyspnoea or both?
  3. Is a patient w/ pneumonia likely the present with an obstructive dyspnoea or restrictive dyspnoea?
  4. Is a patient w/ pneumonia likely to suffer inspiratory dyspnoea, expiratory dyspnoea or both?
A
  1. Obstructive.
  2. Inspiratory.
  3. Restrictive.
  4. Both.
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12
Q

Distant exam of the patient.

A

Assess patient first and stabilise if necessary (O2).
Observe patient’s posture.
Observe patient’s respiratory rate a rhythm.
- inspiratory vs expiratory effort.
- shallow vs laboured.
Listen for:
- URT noise.
– stertor (like snoring) vs stridor.
- wheezing (LRT).

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13
Q

Closer PE.

A

Once stable.
Palpate:
- cranial mediastinum compressibility in cats (gently!)
- thoracic cavity trauma/deformities.
- tracheal pinch.
Assess LNs.

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14
Q

Thoracic auscultation.

A

Auscultate:
- crackles.
- wheezes.
- HR and rhythm: respiratory sinus arrhythmia?
- heart murmur.
- muffled/lack of heart sounds.
Percuss:
- increased/decreases resonance.

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15
Q

Respiratory causes of dyspnoea and tachypnoea?

A

URT:
- obstructive disorders (e.g. laryngeal paralysis / tracheal collapse / BOAS).
LRT:
- obstructive disorders: luminal (e.g. mucus) vs mural (mass or bronchospasm e.g. feline asthma, chronic bronchitis).
Pulmonary parenchyma:
- restrictive disorder / reduced lung capacity e.g. pneumonia, haemorrhage, oedema.
Pleural space:
- restrictive disorder/reduced lung volume: e.g. pleural effusion.
- obstructive disorder e.g. mediastinal mass.

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16
Q

Non-respiratory causes of dyspnoea and tachypnoea.

A

Haematological disorders:
- decreased O2 carrying capacity (anaemia or methaemoglobinaemia).
Metabolic disorders:
- compensatory mechanism to acidosis (DKA).
- muscular weakness (hypokalaemia).
Neurological disorders:
- brain, spinal cord, peripheral nerves.

17
Q

Diagnostic investigations of coughing and dyspnoeic patient.

A

Assess O2:
- SpO2.
- Arterial blood gas analysis.
Blood and faecal tests.
Diagnostic imaging:
- assess pleural space disease.
Laryngeal exam.
Advanced techniques e.g. bronchoscopy.

18
Q

Clinical pathology investigations.

A

Haematology:
- Neutropenia?
- Eosinophilia?
- Thrombocytopenia?
Biochemistry.
Lungworm?
- Angiostrongylus Antigen ELISA (blood test: AngioDetect).
- Faecal smear or Baermann for lungworm.
- Can get false negatives.
- Consider empirical treatment trial w/ fenbendazole or moxidectin.
NT-pro BNP.
- Cardiac vs respiratory cause.
- in pleural effusion (cats).
– negatives reliable.

19
Q

Investigations of cough/dyspnoea under GA.

A

ONCE STABILISED!
Laryngeal exam.
- structure: mass, collapse.
- function: paralysis.
Diagnostic imaging.

20
Q
  1. Which lung pattern is best described as doughnuts and tram lines?
  2. Which lung pattern is best described as cloudy/fluffy/patchy?
  3. Which lung pattern is best described as looking through net curtains?
  4. Which lung pattern is best described by cannon balls.
A
  1. Bronchial.
  2. Alveolar.
  3. Interstitial diffuse.
  4. Interstitial nodular.
21
Q

Diagnostic imaging in the coughing and dyspnoeic patient.

A

Ultrasound:
- thoracic mass?
- E.g. T-FAST techniques (look for thoracic fluid).
Radiography:
- pulmonary patterns (bronchial, alveolar, interstitial).
- heart and vessels.
- masses.
- pleural space.
CT:
- likely referral.

22
Q

Sampling for further investigation.

A

BAL:
- blind or guided by bronchoscope.
- pre-treat cats with Terbutaline.
- cytology.
- bacterial culture.
- Bordetella bronchiseptica and Mycoplasma spp. PCR.
Tracheal wash?
Lung FNA:
- ultrasound-guided.
- peripherally located lesions.

23
Q

Further investigations - bronchoscopy.
Method.

A

Pre-treat cats w/ terbutaline.
Pass through trachea in small patients.
Through ET tube in larger patients.
Look at tracheal mucosal surface.
Tracheal structure.
Facilitate collection of BAL samples.
Removal of FBs.
- can be difficult to retrieve seed head due to spike directions.
- lung lobectomy.

24
Q

Oxygen supplementation options for patients with dyspnoea.

A

Flow-by.
Mask.
Nasal prongs.
Nasal catheter.
Oxygen hood.
Oxygen cage/incubator.
Intubation w/o mechanical ventilation.

25
Q
  1. Advantages of flow-by O2 supplementation.
  2. Disadvantages of flow-by O2 supplementation.
  3. Advantages of mask.
  4. Disadvantages of mask.
A
  1. Useful during initial assessment.
    Easy and well tolerated.
  2. Needs someone to hold the tube.
    Fraction of O2 inhaled by patient is quite low - 25-40%.
  3. Easy.
    Useful for recumbent patient.
  4. Patient may not tolerate.
    Fraction of O2 inhaled by patient not very high - 50-60%.
26
Q
  1. Advantage of nasal prongs.
  2. Disadvantages of nasal prongs?
  3. Advantages of nasal catheters.
  4. Disadvantages of nasal catheters.
  5. Fraction of O2 inhaled by the patient w/ nasal catheters?
A
  1. Easy to place.
  2. Often dislodge - designed for humans.
  3. Can be used longer term.
    Well tolerated.
    Easy access to patient.
    Easy to place.
  4. More invasive / time consuming.
  5. Unilateral = 40%.
    Bilateral = 80%.
27
Q
  1. Disadvantages of O2 hood.
  2. Advantages of O2 cage / incubator.
  3. Disadvantages of O2 cage/incubator.
A
  1. Risk of hyperthermia.
    CO2 build-up.
    Humidity.
    Low fraction of O2 inhaled by patient at 30-40%.
  2. well-tolerated.
    well suited for small patients.
  3. Limited access for patient handling (but may have access via side).
    Need to monitor humidity and temperature.
    Fraction inhaled O2 60% and drops when open door.
28
Q
  1. Indication for intubation w/o mechanical ventilation?
  2. FiO2 w/ intubation w/o mechanical ventilation?
  3. Additional O2 supplementation techniques.
A
  1. Upper airway obstruction.
  2. 100%.
  3. Positive and expiratory pressure.
    Mechanical ventilation.
    Referral.