Prescription review Flashcards

1
Q

what time should diuretics be prescribed?

A

morning!

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2
Q

what time should ACEi be prescribed?

A

evening

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3
Q

drugs that cause constipation? 2 (5)

A
  1. opioids eg: codeine / tramadol
  2. anticholingerics eg: - TCA
    - antihistamines
    - antiparkinsonians
    - neuroleptics
    - bladder instability eg: oxybutyinin
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4
Q

drugs that cause confusion? 3

A

anticholinergics
opioids
benzos eg: diazepam

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5
Q

drugs that cause diarrhoea 7

A
  1. abx
  2. colchicine
  3. lithium
  4. mg containing drugs
  5. metformin
  6. PPI
  7. SSRi
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6
Q

drugs that cause dyspepsia 6

A

NSAIDS / Aspirin
bisphosponates
steroids
macrolides eg: clarithryomycin
metformine
theophylline

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7
Q

drugs that cause falls (dizzy) 3

A
  1. anti- HTN
  2. CNS depressants eg: opiods, benzos, antidepressents, antiphychotics
  3. diuretics
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8
Q

drugs that cause hearing loss 4

A

aminoglycosides eg: gent

cisplatin

loop diuretics eg: furosemide

PD5i eg: talalafil

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9
Q

drugs that cause tremor 5

A

beta 2 agonist eg: salbutamol

ciclosporin

levothyroxin

lithium

nicotine

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10
Q

drugs contraindicated in PUD? 2

A

nsaids
aspirin

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11
Q

drugs contraindicated in CKD? 3

A

nsaids
ACEi
reduced clearance of gent / digoxin

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12
Q

drugs contraindicated in chronic heart failure 5

A

CCB eg: verampil
flecainide
TCA
nsaids
steroids

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13
Q

drugs contrindicated in asthma 2

A

beta blockers
nsaids

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14
Q

drugs contraindicated in heart block 3

A

digoxin
bb
verampil

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15
Q

drugs contraindicated in Parkinsons 2

A

metoclopramide
haloperidol

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16
Q

dietary interaction with warfarin?

A

vitamin K rich foods eg: spinahc reduce anticoauglant affect of warfarin

17
Q

dietary interaction with statins?

A

grapefruit juice = inhibit metabolism increasing adverse effects

18
Q

dietary interactions with MAOIs?

A

picked/ cured foods => HTN crisis

19
Q

drugs that cause high BP 5

A

steroids
ciclosporin
nsaids
ostrogen
venlafexine

20
Q

drugs that cause bradycardia 3

A

BB
CCB eg: verampil
digoxin

21
Q

drugs that cause extrapyramidal movements 4

A

DOPAMINE ANTAGONISTS

  1. first gen antiphyschotics eg: haloperidol
  2. second gen AP eg: chlorpromazine
  3. anti-emetics eg: prochlorperazine / metoclopramide
  4. SSRI eg: fluoxetine
22
Q

drugs that cause tremor 3

A

beta 2 agonist eg: salbtaumol

theophyillines

thyroid hormones

23
Q

drugs associated with bruising? 3

A

anticoagulants eg: LMWH/ DOAC/ warfarin

antiplatelets eg: aspirin/ clopidorl

steroids

24
Q

Drugs that can cause fall in Hb ?4

rise in hb? 1

A
  1. nsaids = damage gastric mucosa
  2. anticoagulants
  3. methyldopa = haemoylsis
  4. impaired EPO = chemo
  5. polycythaemia = steroids
25
Q

drugs that cause leucopenia (low) 10

A
  1. carbimazole = anti thyroid
  2. chemo
  3. antimetabolites
  4. phenothiazines
  5. antiHTN
  6. anti histamines
  7. MAB
  8. anticonvulsant eg: carbamezapine
  9. antipsychotics
  10. abx
26
Q

drugs that reduce platelet count?

A

Herparin

nsaids

quinine

trimethoprime / sulfamethazole

vancomycin

peniclline

rifampicin / carbamezepine

27
Q

drugs impair liver function? 5

A

amiodarone

AED eg: phenytoin / sodium val

anti - TB eg: isoniazid

paracetamol

statins

28
Q

signs of digoxin toxicity

A

bradycardia
nausea
vomitting
diarrhoea

29
Q

what electrolyte disturbance worsens digoxin toxicty >

A

hypoK

30
Q

medications unsafe in pregnancy 3

A

ACEI/ ARB
Statins
warfarin

31
Q

drug interactions with statins? 5

A

clarithromycin
grapefruit juice
ciclosproin
verampil
fenofibrate

32
Q

drugs interacting with warfarin? 5

A

amiodarone
antifungals eg: fluconazole
ciprofloxacin
clarithromycin
nsaids

33
Q
A