Prescription review

Question 1

what time should diuretics be prescribed?

Answer 1

morning!

Question 2

what time should ACEi be prescribed?

Answer 2

evening

Question 3

drugs that cause constipation? 2 (5)

Answer 3

1. opioids eg: codeine / tramadol
2. anticholingerics eg: - TCA
   - antihistamines
   - antiparkinsonians
   - neuroleptics
   - bladder instability eg: oxybutyinin

Question 4

drugs that cause confusion? 3

Answer 4

anticholinergics
opioids
benzos eg: diazepam

Question 5

drugs that cause diarrhoea 7

Answer 5

1. abx
2. colchicine
3. lithium
4. mg containing drugs
5. metformin
6. PPI
7. SSRi

Question 6

drugs that cause dyspepsia 6

Answer 6

NSAIDS / Aspirin
bisphosponates
steroids
macrolides eg: clarithryomycin
metformine
theophylline

Question 7

drugs that cause falls (dizzy) 3

Answer 7

1. anti- HTN
2. CNS depressants eg: opiods, benzos, antidepressents, antiphychotics
3. diuretics

Question 8

drugs that cause hearing loss 4

Answer 8

aminoglycosides eg: gent

cisplatin

loop diuretics eg: furosemide

PD5i eg: talalafil

Question 9

drugs that cause tremor 5

Answer 9

beta 2 agonist eg: salbutamol

ciclosporin

levothyroxin

lithium

nicotine

Question 10

drugs contraindicated in PUD? 2

Answer 10

nsaids
aspirin

Question 11

drugs contraindicated in CKD? 3

Answer 11

nsaids
ACEi
reduced clearance of gent / digoxin

Question 12

drugs contraindicated in chronic heart failure 5

Answer 12

CCB eg: verampil
flecainide
TCA
nsaids
steroids

Question 13

drugs contrindicated in asthma 2

Answer 13

beta blockers
nsaids

Question 14

drugs contraindicated in heart block 3

Answer 14

digoxin
bb
verampil

Question 15

drugs contraindicated in Parkinsons 2

Answer 15

metoclopramide
haloperidol

Question 16

dietary interaction with warfarin?

Answer 16

vitamin K rich foods eg: spinahc reduce anticoauglant affect of warfarin

Question 17

dietary interaction with statins?

Answer 17

grapefruit juice = inhibit metabolism increasing adverse effects

Question 18

dietary interactions with MAOIs?

Answer 18

picked/ cured foods => HTN crisis

Question 19

drugs that cause high BP 5

Answer 19

steroids
ciclosporin
nsaids
ostrogen
venlafexine

Question 20

drugs that cause bradycardia 3

Answer 20

BB
CCB eg: verampil
digoxin

Question 21

drugs that cause extrapyramidal movements 4

Answer 21

DOPAMINE ANTAGONISTS

1. first gen antiphyschotics eg: haloperidol
2. second gen AP eg: chlorpromazine
3. anti-emetics eg: prochlorperazine / metoclopramide
4. SSRI eg: fluoxetine

Question 22

drugs that cause tremor 3

Answer 22

beta 2 agonist eg: salbtaumol

theophyillines

thyroid hormones

Question 23

drugs associated with bruising? 3

Answer 23

anticoagulants eg: LMWH/ DOAC/ warfarin

antiplatelets eg: aspirin/ clopidorl

steroids

Question 24

Drugs that can cause fall in Hb ?4

rise in hb? 1

Answer 24

1. nsaids = damage gastric mucosa
2. anticoagulants
3. methyldopa = haemoylsis
4. impaired EPO = chemo
5. polycythaemia = steroids

Question 25

drugs that cause leucopenia (low) 10

Answer 25

1. carbimazole = anti thyroid 2. chemo 3. antimetabolites 4. phenothiazines 5. antiHTN 6. anti histamines 7. MAB 8. anticonvulsant eg: carbamezapine 9. antipsychotics 10. abx

Question 26

drugs that reduce platelet count?

Answer 26

Herparin nsaids quinine trimethoprime / sulfamethazole vancomycin peniclline rifampicin / carbamezepine

Question 27

drugs impair liver function? 5

Answer 27

amiodarone AED eg: phenytoin / sodium val anti - TB eg: isoniazid paracetamol statins

Question 28

signs of digoxin toxicity

Answer 28

bradycardia nausea vomitting diarrhoea

Question 29

what electrolyte disturbance worsens digoxin toxicty >

Answer 29

hypoK

Question 30

medications unsafe in pregnancy 3

Answer 30

ACEI/ ARB Statins warfarin

Question 31

drug interactions with statins? 5

Answer 31

clarithromycin grapefruit juice ciclosproin verampil fenofibrate

Question 32

drugs interacting with warfarin? 5

Answer 32

amiodarone antifungals eg: fluconazole ciprofloxacin clarithromycin nsaids