Planning management / ADR Flashcards

1
Q

management of acute mania / hypomania

A

antipyschotics eg: onlazapine / haloperidol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

management of acute agitation / anxiety?

A

benzodiazepines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

management of pyelonephritis

A

IV ABX eg: ceftriaxone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

mx of anaphylaxis

A

1:1000 IM 0.5mg adrenaline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

how does bronchiolitis present?

A

<1 year

coryza
wheeze
mild fever!
increased WOB
dry cough

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

mx of bronchiolitis?

prophylaxis?

A
  1. supportive eg: oxygen
    - headbox
    - nasal canula
  2. IV fluids

palivizumab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

presentation of croup?

management?
mild
moderate
severe?

A

barking cough worse at night, temperature, stridor, resp distress, coryza

Mx:
All severity = one off dose of oral dexamethasone (0.15mglg)

mild = at home
moderate / severe= admit

moderate / severe= nebulised adrenaline / budenoside

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

drug management of cardiac arrest shockable rhythms
= VF / pulseless VT

A
  1. adrenaline 1mg after the 3rd shock then after 5/ 7 th shock
  2. amiodarone after 3rd shock 300mg IV
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

drug management of non shockable rhythm PEA / asystole

A

adrenaline 1mg IV / IO 3rd/5th/7th

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

drug mx of dvt?

A

DOAC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

mx of emergency hypoglcyaemia

A

20% glucose 100ml OVER 15 m

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

mx of DKA?

A

IV fluids eg:
1L 0.9% NaCl over 1 hour

1L 0.9% NaCl+ KCL over 2 hours -> 2 -> 4 -> 4

fixed rate insulin infusion 0.1units /kg/ hour

once BG < 14 = 10% dextrose infusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

mx of HHS?

A

1L over 1 hour

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

mx of hyperK

A

IV 10% calcium gluconate 10 ml

Insulin / dextrose infusion (10 units actrapid + 25g glucose)

nebulised salbutamol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

how to find management of status elipticus?

A

under epilepsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

mx of status elipticus

A

buccal midazol / rectal diazepam community

IV 4mg lorazepam

IV 4mg lorazepam (2 doses benzo 10mins apart)

Iv pheynytoin / sodium valproate

RSI eg: propofol / midazol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

mx of pneumonia CAP
CURB 1 + pen allergic?

CURB 2

CURB 3

A
  1. amoxicillin
    PA : doxycline/ clarithromycin
  2. amoxicillin + clarithryomcin oral
  3. IV co-amoxiclav + clarithromycin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

mx of HAP

A
  1. oral co-amox
  2. IV taz
  3. mrsa = vacno
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

mx of sickle cell crisis

A

analgesia eg: opiates

hydration

oxygen

blood transfusion

exchange transfusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

what to type in for alcohol syndromes?

A

alcohol dependence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

mx of alcohol withdrawal

A

chlordiazepoxide reducing regimen

22
Q

mx of delirium tremens

A

benzo eg: lorzepam

23
Q

mx of wernickes encephalothpyg

A

pabrinx IV thiamine

24
Q

where to find management of gynae infections?

A

genital infections

25
Q

where to find anti-emetics

A

under nausea

26
Q

mx of PMR?

A

15mg oral prednisolone

27
Q

mx of BPH?

A

alpha blocker eg: tamsulosin

5 alpha reductase inhbitors eg: finasteride

28
Q

drug mx of conjunctivtis

A

chloramphenicol eye drops 0.5%
fusidic acid

29
Q

calcium / vitmain D + bisphoonates how to take?

A

at least 4 hours apart - calcium interferes with absorption of bisohposonates

30
Q

what are the MHRA/ CHM warnings?

A

less common but more serious adverse effects to look out for

31
Q

advice for use of amiodarone?

A

wear suncream

32
Q

ADR of loop diuretics? 4

A

dehydration
renal impairment
hypoK
otoxicity

33
Q

ADR of NSAIDS? 3

A

PUD
renal impairment
HTN

34
Q

ADR of opioids 5

A

urinary retention
constipation
drowsy
confusion
sedation

35
Q

2 drugs that interact with warfarin and increase INR?

A

clarityhromycin
amiodarone

36
Q

example of drugs that require plasma drug concentration monitoring

A

lithium
dixogin
gentamicin
vancomycin
phenytoin

37
Q

when are lithium samples taken?

range?

A

6 hours post dose
0.4-1

38
Q

when are gentamicin levels taken?

A

6-14 hours post dose for once daily regimen

39
Q

when are vancomycin levels taken?

A

pre dose (trough) = taken after 3-4 doses

40
Q

when should digoxin smaples be taken?

how is efficacy determined?

A

6 hours post dose

HR

41
Q

example of drugs which renal function will have an influence on the initial or maintenance dosage

A

DOAC eg: apixaban should be halved if creatinin clearance 15-29

co-amox = dosing interval extended if egfr 10-30

venlafaxine = maintenance dose half if egfr <30

42
Q

statins and LFT?
what is safe to continue?

A

if AST/ALT less than x3 upper limit = safe to continue

43
Q

drugs that affect LFT

A

amiodarone
MTX
statins
terbinafine

44
Q

drugs that cause hypoNa 6

A
  • thiazide diuretics / loops diuretics
  • TCAs
  • SSRi
  • antipsychotics eG: haloperidol
  • Anti epiletics eg: carbmazeapine
  • PPI
45
Q

drugs that cause hypoK 5

A

thiazide and loop diruetics

mieralcorticoids eg: fludrocortisone

insulin

beta 2 agonists eg: salbutamol

chronic use of laxatives

46
Q

drugs that cause hyperK 6

A

K+ sparing diuretics eg: spiro

ACEi / ARB

NSAIDS

ciclosporin

tacrolimus

trimethorpime

47
Q

target blood concentration for diabetes

A

6-10 (4-12 ok)

48
Q

Mx of high INR: BLEEDING

  1. major bleeding
  2. minor bleeding and iNR > 8
  3. minor bleeding INR 5-8
A

Bleeding

  1. stop warfarin - IV vitamin K - PTComplex / FFP
  2. Stop warafrin - IV vitamin K - repeat INR 24 horus - repeat vitamin K - restart warfarin when INR < 5
  3. STOP warfarin - IV vitamin K, restart warfarin INR < 5
49
Q

Mx of high INR: no bleeding

  1. INR > 8
  2. INR 5-8
  3. BLEEDING INR normal
A
  1. sto warfarin- oral vitamin K - repeat INR 24 hours - restart warfarin < 5
  2. withhold 1-2 doses of warfarin and reduced subsequent maintenance dose
  3. investigate underlying cause
50
Q

how to control overnight glycaemic control? ie : high BMs in the morning?

A

increase long acting in prior evening

51
Q

lithium + ACEi?

A

interact = increased serum lithium concentration

reduce lithium levels by 1/3 or 1/2

52
Q
A