Prescribing

Question 1

ACE inhibitor suffix

Answer 1

pril

Question 2

Statin side effects

Answer 2

Muscle aches/cramps

Question 3

HTN

BP cutoffs

Answer 3

140/90 - grade 1 (mild) HTN
160/100 - grade 2 (moderate) HTN
>180/110 - grade 3 (severe) HTN

Question 4

HTN

Secondary Causes

Answer 4

ABCDE
Accuracy of diagnosis, Apnoea (OSA), Aldosteronism
Bruits (renal artery stenosis), Bad kidneys (renal parenchymal disease)
Catecholamines (excess), Coarctation of the aorta, Cushing’s syndrome
Drugs, Diet
EPO (excess), Endocrine disorders

Question 5

HTN

Treatment

Answer 5

1st line - ACEi/ARB, Calcium channel blocker, Thiazide diuretic, Betablockers
2nd line - K sparing diuretics, alpha blockers, centrally acting antiadrengeric drugs, direct acting vasodilators

Question 6

Statins

Answer 6

HMG-CoA reductase inhibitors

Decrease cholesterol synthesis and LDL

Question 7

Ezetimibe

Answer 7

Decreases absorption of cholesterol across intestinal wall and decreases LDL
Added to statins or instead of statins if they aren’t tolerated

Question 8

Hypercholesterolaemia

Treatment

Answer 8

6 month trial of lifestyle change (unless symptomatic)
Statins
+/or ezetimibe
or fenobibrate

Question 9

Fenobibrate

Answer 9

3rd line treatment for hypercholesterolaemia
1st line for isolated hypertriglyceridaemia
Not well tolerated