Prenatal Diagnosis, Fetal Therapy And Ultrasound Flashcards

1
Q

An intrinsic abnormality programmed in development, spina bifida and omaphalocele

A

Malformation

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2
Q

When a genetically normal fetus develops abnormally because of mechanical features

A

Deformation

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3
Q

Occurs when genetically normal tissue is modified as the result of a specific result

A

Disruption

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4
Q

A cluster of several anomalies or defects that have the same cause

A

Syndrome

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5
Q

These defects has ancephaly, spina bifida, cephalocele and rare spinal cases

A

Open neural tube defect

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6
Q

What are examples of anti folate antibodies

A

Anti convulsants

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7
Q

Amount of folic acid must be taken before first trimester

A

4mg

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8
Q

Sources of AFP

A

fetal yolk sac

Fetal git and liver

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9
Q

When does the concentration fetal serum and amniotic fluid increase

A

13th week

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10
Q

When is maternal serum afp offered

A

Second trimester

15-20 weeks

<2-2.5 normal

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11
Q

What are the factors that influence Maternal serum levels

A
Maternal weight
Gestational age
Race
Diabetes 
Multifetal gestation
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12
Q

Low levels of AFP ee

A
Obesity
DM
Trisonomy 21 and 18
Gestational trorphoblastic diese
Overestimated gestational age
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13
Q

What are the 5 specific cranial anomalies

A
Frontal bone scalloping, lemon sign
Small biparietal diameter
Ventriculomegaly
Obliteration or the cistern magna
Elongated cerebellum, banana sign
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14
Q

1st trimester down syndrome screening

A

Maternal serum testing
Nuchal translucency
Combination

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15
Q

Nuchal measurement considered normal

A

3.5mm

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16
Q

Second trimester screning

A

Triple test

AFP
HcG
Unconjugated estriol

Quad
Triple
Dimeric inhibin alpha

17
Q

Sonographic markers of down syndrome

A

Nuchal skin fold
Renal pelvis dilation
Echogenic intracardiac
Echogenic bowel

18
Q

How many ml of amniotic fluid do you usually get

19
Q

Percutaneous umbilical cord blood sampling is also known as

A

Cordocentesis

20
Q

Clinical application of ultrasound

A

Accurate pregnancy dating

Detection of fetal anomalies

21
Q

When is the optimal time to determine chorionicity

Evaluate uterus, adnexal structures and cul de sac

A

1st trimester

22
Q

at what week you can do transabdominal scanning of gestational sac

23
Q

Components or standard ultrasound during 1st trimester

A

Embryo

Crown rump length

Cardiac activity

Fetal number

24
Q

When is fetal biometry done

A

2nd and 3rd trimester

25
If the head shape is flattened what does is signify
Dolichocephaly
26
Most affected by fetal growth
Abdominal circumference
27
Normal value of amniotic fluid index
5 to 24 cm
28
Used to determine the volume and rate of blood flow through maternal and fetal vessels
Doppler velocimetry
29
Diminished blood flow may be reflectd such as the following
Diastolic notch Increased sd ratio Pulsatiliry index Absence or reverse blood flow
30
When MCA is increased, what does the px have
fetal anemia