Placental hormones Flashcards
At what chromosome is HCG seen
Chromosome 6
Can influence hCG production in trophoblast
IL6
EGF
cAMP
Blood levels are increases in what manner
Doubling every 3 days
Maximal levels attained at what week
8-10 weeks
At what week of hCG declines
10-12
When does Nadir happen
16 weeks
Function of hCG
Rescue and maintain of function of the corpus luteum
Stimulation of fetal testicular test is and maternal thyroid activity
Relaxin secretion
Uterine vasodilation and uterine contraction
Other name of hPL
Human chorionic somatomammotropin
Chorionic growth hormone
HPL is detected at what week
2nd or 3rd week
What is the production rate of hPL
1g per day
This inhibits leptin
HPL
Function of hPL
Maternal lipolysis
Anti insulin
Potent angiogenic hormone
Cortisol release hormone is important for
Controlling fetal lung maturity
Timing of parturition
This promotes uterine Relaxtion and quiescence in early pregnancy
Relaxin
This is an anti obesity hormone
Leptin
This inhibits pituitary FSH release
Inhibin
This enhances FSH synthesis and secretion and participates in the regulation of the menstrual cycle
Activin
When does the placenta replace the ovary as the source of progesterone
8th week
Source of the placenta for progesterone formation
Exogenous cholesterol
Trophoblast uses what for progesterone biosynthesis
LDL cholesterol
Important precursor for synthesis and metabolism in human decidua and fetal membrane
Pregnenolone sulfate
Most important source of placental estrogen precursor in human pregnancy
Fetal adrenal cortex
