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Physio OB > Placental hormones > Flashcards

Placental hormones Flashcards

1
Q

At what chromosome is HCG seen

A

Chromosome 6

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2
Q

Can influence hCG production in trophoblast

A

IL6
EGF
cAMP

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3
Q

Blood levels are increases in what manner

A

Doubling every 3 days

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4
Q

Maximal levels attained at what week

A

8-10 weeks

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5
Q

At what week of hCG declines

A

10-12

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6
Q

When does Nadir happen

A

16 weeks

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7
Q

Function of hCG

A

Rescue and maintain of function of the corpus luteum

Stimulation of fetal testicular test is and maternal thyroid activity

Relaxin secretion

Uterine vasodilation and uterine contraction

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8
Q

Other name of hPL

A

Human chorionic somatomammotropin

Chorionic growth hormone

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9
Q

HPL is detected at what week

A

2nd or 3rd week

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10
Q

What is the production rate of hPL

A

1g per day

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11
Q

This inhibits leptin

A

HPL

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12
Q

Function of hPL

A

Maternal lipolysis

Anti insulin

Potent angiogenic hormone

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13
Q

Cortisol release hormone is important for

A

Controlling fetal lung maturity

Timing of parturition

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14
Q

This promotes uterine Relaxtion and quiescence in early pregnancy

A

Relaxin

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15
Q

This is an anti obesity hormone

A

Leptin

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16
Q

This inhibits pituitary FSH release

A

Inhibin

17
Q

This enhances FSH synthesis and secretion and participates in the regulation of the menstrual cycle

A

Activin

18
Q

When does the placenta replace the ovary as the source of progesterone

A

8th week

19
Q

Source of the placenta for progesterone formation

A

Exogenous cholesterol

20
Q

Trophoblast uses what for progesterone biosynthesis

A

LDL cholesterol

21
Q

Important precursor for synthesis and metabolism in human decidua and fetal membrane

A

Pregnenolone sulfate

22
Q

Most important source of placental estrogen precursor in human pregnancy

A

Fetal adrenal cortex

Physio OB (12 decks)

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