prenatal development Flashcards

Lecture 2/22

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1
Q

what % of organisms that have a spinal cord (chordates) have a bony sheath / skeletal

A

97%

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2
Q

due to humans having spinal cords which group of organisms does it make us a member of

A

chordates

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3
Q

how many species of chordates are there

A

around 6,000 in the world

and in terms of biodiversity amongst other living things there is a actually only a few of us - scientists have named 2 million different species

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4
Q

early scientific views on prenatal development

A

1590s - invention of microscope

1695 - Nicalaas Hartsoeker and the performation theory of development

19th century - improvements in optics had demonstrated that embryonic development did not involve simple processes of growth but also substantial differentiation.

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5
Q

Nicolass Hartsoeker

A

1695
the preformation theory of development

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6
Q

the preformation theory of development

A

nicolaas Hartsoeker - 1695

looked at sperm under a microscope and saw that in the inside of it looked to be a human shaped element

led to the idea if preformation - the idea that development is entirely a matter of growth and the womb acts as place for this expansion to happen within

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7
Q

aristotle - 384-322 b.c.

A

scala naturae - great chain of being species are fixed and arranged hierarchically

with humans at the top of the scale / ladder of creation

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8
Q

an incorrect idea of evolution

A

that it is a directional process - a straight line from point a to point b

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9
Q

what is the recapitulation theory

A

based on aristotle idea of ladder of creation

suggested that the embryo took the form of adult animals further down on the ladder of creation

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10
Q

stages of recapitulation theory

A

fish phase - suggested due to theorists seeing that human embryos went through a fish like phase

followed by salamander stage of development

etc. tortoise, chick, hog, calf and rabbit before achieving the final goal

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11
Q

stages of prenatal development

A
  1. the germinal period - conception to implantation
  2. the period of the embryo - implantation to 2 months roughly
  3. the period of the fetus - 2 months to birth
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12
Q

germinal period

A

sperm cell fertilizes an egg in the fallopian tube

zygote moves down the fallopian tube and into the uterus

4 days after conception the zygote multiplies to form a mass of cells called a mortula

after this the daughter cells decrease and decrease to leave a spherical mass of identical cells called stem cells (can grow into any type of tissue) in this stage the embryo is a blastocyst

finally the embryo implants on the uterus wall

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13
Q

what is a mortula

A

when the zygote multipies to form a mass of cells

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14
Q

what is a blastocyst

A

is a stage where the embryo is around 150 cells and has stem cells
happens at around 3 to 5 days

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15
Q

period of the embryo - stage of implantation

A

happens around 8 weeks post conception

the blastocyst now differentiates into 3 distinct layers of different tissue types as each of these layers develop the become different major organ systems

last 2 months

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16
Q

the 3 types of blastocyst tissue

A

ectoderm - top layer - nervous system, teeth, finger, nails and outer layer of skin

mesoderm - middle layer - muscles, bones and circulatory system and inner surface of the skin

endoderm - bottom layer - gastrointestinal tracks and major organs e.g. lungs and glands

17
Q

period of the fetus

A

this period is concerned with growth as most organs are developed
the liver is already developed and the eyes continue to develop as the brain grows

featus will respond to stimulation at this stage

hearing develops at 20 weeks

4 months there is motor development - movements such as sucking their thumb

by the end of this period featus respond with movement or heart rate changes to temperature changes or touch

18
Q

when does hearing develop

A

20 weeks - can detect low frequency sounds of around 250 to 550 hertz

(very narrow hearing band - adults = 20 to 20,000 hertz)

range of a voice

19
Q

variations from typical development statistic

A

world health organisation

orgins of congenital aberrations are unknown in 50% of cases

20
Q

genetics part in variation from typical development

A

Cystic fibrosis
sickle cell anemia
various chromosomal disorders

21
Q

environment part in variation from typical development

A

toxins - thalidomide, alcohol, radiation, pesticides

nutrition - folic acid

22
Q

how many chromosomes do we inherit from our parents

A

46 - 23 from each parent

23
Q

the process of cell dividing in half

A

mitosis

(supports growth)

24
Q

mitosis

A

prophase - duplicate chromosomes in cell

metaphase - chromosomes align at the metaphase plate

anaphase telophase - sister chromatids separate coursing two cells with the same genetic code to exist

25
Q

Meiosis

A

happens during the creation of the egg and sperm

so once division has ended you end up with daughter cells that half the original number of chromosomes

26
Q

human karyotypes

A

the pictation of chromosomes

27
Q

chromosomal variations

A

aneuplodiy - the condition of having fewer or more chromosomes than the usual number coursing developmental issues and learning difficulties

down syndrome - trisomy 21

edwards syndrome - trisomy 18

patau syndrome - trisomy 13

28
Q

chromosomal variations in the sex chromosome

A

there are lot of different variations that are compatible with life leading to intersex individuals

a lot more than just xx or xy

29
Q

define teratogens

A

are substances that cause birth defects
only effect the fetus affect the implantation phase due to a shared blood supply

30
Q

the thalidomide tragedy

A

drug developed in 1954 - to treat headaches, insomnia and morning sickness

by 1961 - the drug had led to 20,000 children in 46 different countries being effected by birth defects such as severely misshapen limbs

only effected children if prescribed during the 1st trimester as the limbs can only be effected during embryo period

31
Q

fetal alcohol syndrome

A

course by alcohol effecting the development of the central nervous system

cause unusual facial structure and an under developed brain
children have difficulties with vision and hearing plus face learning difficulties

32
Q

DeCasper and spence - 1986

A

fetal learning
N=16 gestation age 7.5 months

read stories 2x a day

tested at 2.5 days after birth
half hear same stories after fast sucking of the dummy and half hear it after slow sucking

result - babies showed preference for familiar stories as they

33
Q

hepper 1991

A

neighbors - soap show
sampled mothers who religiously watch the show and those who didn’t

look for difference in their babies when playing the stimulus (show intro) after they were born

found clear difference in the movements of the learning group