Prenatal Flashcards by Andrew McCarty

Q

AFP affected by

A

race, wt, DM(lower)

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Q

Quad screen when

A

16-17 weeks (15-18 up to 20)

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Q

A-thal is in what pops

A

SE Asia, China

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Q

B thal in what pops

A

Africa, SEAsia

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Q

SMA cyto location

A

5q11`

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Q

when is safe from teratogens

A

6-9days

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Q

Penicillamine tet effect

A

cutis laxa

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Q

rubella, highest risk time

A

1-3 mo`

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Q

syphillias tet effect

A

W-teeth, plaques, skin, CNS

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Q

carbazepine)anti convulsant

A

ONTDs

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Q

DM tet effect

A

CHD, NTD, limb, holopros

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Q

3 IMPORTANT ASSESS OF TERATOGEN

A

TIMING, DOSE, INDICATION

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Q

CUTOFF FOR HIGH RISK

A

1/270

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Q

PaPPA performed when?

A

10-12wks

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Q

1st tri screen when

A

11-14wks

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Q

integrated resulted when

A

1st plus 2nd, given in 2nd

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Q

Sequential resulted when

A

resulted 1st and 2nd

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Q

CMV

A

IUGR, eye, ear brain

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Q

HPV

A

slpapped cheek, arthritis

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Q

Rubela risk when

A

1-3 month

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Q

syphillias

A

w teeth plaques, CNS

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Q

androgens

A

ambiguosu genetalia in girls

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Q

hydantoin

A

NAILS, dd,GROWTH delay

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Q

DM

A

CHD NTD limb holopro

Q

safe period in preg

A

6-9days

Q

A thal screened in

A

SE asia, S china

Q

B thal screened in

A

Africa, SE asia

Q

NDJ risk aat 20

A

1500

Q

NDJ risk at 35

A

1/400

Q

NDJ risk @ 40

A

1/100

Q

% DS abort

A

75%

Q

Kleinfelter primarily what error

A

M1 male

Q

TUrner risk

A

1/1500

Q

RObertsonian risk

A

1/1000

Q

reciprocal translocation risk

A

1/500

Q

kleinfelter errors?

A

Male M1 50%

Q

Recip trans risk

A

20%RR if prev child
4% if SABs x n
8% if dx prenatally

Q

MSAFP detects ONTDS %

A

90

Q

MSAFP test when

A

16-18 optomal , 15-20 sub opt

Q

first tri screen done?

A

9-13.6

Q

1st tri detection

A

90%

Q

Nt done

A

11-13.6

Q

2nd tri screen when

A

15-20

Q

2nd tri detection

A

80%

Q

stepwise given

A

1st and 2nd serum or dx ifhigh

Q

before 20 wks

A

offer ONTD

Q

if before 14

A

offer 1st tri

Q

if done CVS 1st tri

A

still offer NTD

Q

NT above 3.5

A

prompt US echo

Q

DS risk SDR

A

none inc

Q

rob13q21q risk

A

15% mom, .5dad for 21 also 13

Q

rob 14q21q risk

A

15 mom, 1% dadalso UPD 14

Q

amnio risk

A

1/300

Q

cvs risk

A

1/100-200

Q

integrated # when

A

2 visits result in second 96%

Q

stepwise

A

stratefied 2 visits

Q

NIPT tested when

A

10.-21

Q

US done when

A

10.4-13.6 +