Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Backup 2 > Prelim drugs > Flashcards

Prelim drugs Flashcards

1
Q

Drug Name

A 
Drug Class
Mechanism
Distinguishing Chem Characteristics (Unique or "weird" features)
Pharmacological characteristics
Side Effects
Special side effects
Use
[mnemonic] (put in brackets)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

cyclophosphamide

A

-alkylating agents (bischoloroethyl amines)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

mechlorethamine

A

-alkylating agents (bischoloroethyl amines)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

nitrosureas

A

-alkylating agents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

procarbazine

A

-alkylating agents (other)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

cisplatin

A

-platinum coordination complexes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

methotrexate

A

-anti-tumor antimetabolites

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

leucovorin

A

-anti-tumor antimetabolites (folinic acid rescue)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

5-fluorouracil

A
  • anti-tumor antimetabolites

- pyrimidine antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

capecitabine

A
  • anti-tumor antimetabolites

- pyrimidine antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

cytosine arabinoside (cytarabine, ara C)

A
  • anti-tumor antimetabolites

- pyrimidine antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

6-mercaptopurine

A
  • anti-tumor antimetabolites

- purine antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

6-thioguanine

A
  • anti-tumor antimetabolites

- purine antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

bleomycin

A

-anti-tumor antibiotics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

daunorubicin

A

-anti-tumor antibiotics, topoisomerase inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

doxorubicin

A

-anti-tumor antibiotics, topoisomerase inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

paclitaxel

A

-mitotic spindle poisons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

vinblastine

A

-mitotic spindle poisons (vinca alkaloids)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

vincristine

A

-mitotic spindle poisons (vinca alkaloids)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

irinotecan

A

-topoisomerase inhibitors (camptothecins)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

topotecan

A

-topoisomerase inhibitors (camptothecins)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

daunorubicin

A

-anti-tumor antibiotics, topoisomerase inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

doxorubicin

A

-anti-tumor antibiotics, topoisomerase inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

etoposide

A

-topoisomerase inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

tamoxifen

A

-antagonist of hormone action

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

raloxifene

A

-antagonist of hormone action

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

anastrozole

A

-antagonist of hormone action

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

letrozole

A

-antagonist of hormone action

29
Q

exemestane

A

-antagonist of hormone action

30
Q

leuprolide

A

-antagonist of hormone action

31
Q

flutamide

A

-antagonist of hormone action

32
Q

prednisone

A

-adrenocorticosteroids

33
Q

lapatinib

A

-“Targeted” agents (EGFR kinase inhibitors)

34
Q

erlotinib

A

-“Targeted” agents (EGFR kinase inhibitors)

35
Q

lapatinib

A

-“Targeted” agents (HER2 kinase inhibitor)

36
Q

imatinib

A

-“Targeted” agents (bcr/abl kinase inhibitor)

37
Q

cetuximab

A

-“Targeted” agents (chimeric/humanized antibodies)

38
Q

trastuzumab

A

-“Targeted” agents (chimeric/humanized antibodies)

39
Q

brentuximab vedotin

A

-“Targeted” agents (chimeric/humanized antibodies)

40
Q

Drug Name

A 
Drug Class
Mechanism
Distinguishing Chem Characteristics (Unique or "weird" features)
Pharmacological characteristics
Side Effects
Special side effects
Use
[mnemonic] (put in brackets)
41
Q

Morphine

A

-Opioid agonist
-Mu receptor
-
-
-sedate, constipate, resp depress, nausea/vomit
-euphoria, miosis
-Analgesia

42
Q

Drug Name

A 
Drug Class
Mechanism
Distinguishing Chem Characteristics (Unique or "weird" features)
Pharmacological characteristics
Side Effects
Special side effects
Use
[mnemonic] (put in brackets)
43
Q

amitriptyline

A
  • tricyclics (TCA’s)
  • block ser & NE reuptake
  • block histamine, muscarinic, adrenergic R’s.
  • 2 weeks to work, long half-life, kidney elim & bit hepatic microsomes
  • antimuscarinic, sedation (H1 R), sex down, weight up, delirium, tachycardia
  • seizures, slowing A-V conductance, orthostatic hypotension (alpha 1 R)
  • Antidepressant
44
Q

amoxapine

A
  • tricyclics (TCA’s)
  • block ser & NE reuptake
  • block histamine, muscarinic, adrenergic R’s.
  • 2 weeks to work, long half-life, kidney elim & bit hepatic microsomes
  • antimuscarinic, sedation (H1 R), sex down, weight up, delirium, tachycardia
  • seizures, slowing A-V conductance, orthostatic hypotension (alpha 1 R)
  • Antidepressant
45
Q

imipramine

A
  • tricyclics (TCA’s)
  • block ser & NE reuptake
  • block histamine, muscarinic, adrenergic R’s.
  • 2 weeks to work, long half-life, kidney elim & bit hepatic microsomes
  • antimuscarinic, sedation (H1 R), sex down, weight up, delirium, tachycardia
  • seizures, slowing A-V conductance, orthostatic hypotension (alpha 1 R)
  • Antidepressant
46
Q

nortriptyline

A
  • tricyclics (TCA’s)
  • block ser & NE reuptake
  • block histamine, muscarinic, adrenergic R’s.
  • 2 weeks to work, long half-life, kidney elim & bit hepatic microsomes
  • antimuscarinic, sedation (H1 R), sex down, weight up, delirium, tachycardia
  • seizures, slowing A-V conductance, orthostatic hypotension (alpha 1 R)
  • Antidepressant
47
Q

citalopram

A
  • SSRI’s
  • block ser reuptake
  • neurogenesis in hippocampus (via BDNF)
  • 2 wks to work, kidney elim, block P450, high first-pass effect, binds plasma proteins
  • nausea, anxiety, insomnia… late: sex down
  • late: anorexia, mania
  • Antidepressant
48
Q

escitalopram

A
  • SSRI’s
  • block ser reuptake
  • neurogenesis in hippocampus (via BDNF)
  • 2 wks to work, kidney elim, block P450, high first-pass effect, binds plasma proteins
  • nausea, anxiety, insomnia… late: sex down
  • late: anorexia, mania
  • Antidepressant
49
Q

fluoxetine

A
  • SSRI’s
  • block ser reuptake
  • neurogenesis in hippocampus (via BDNF)
  • demethylated to active. 2 wks to work, kidney elim, block P450, high first-pass effect, binds plasma proteins
  • nausea, anxiety, insomnia… late: sex down
  • late: anorexia, mania
  • Antidepressant
50
Q

sertraline

A
  • SSRI’s
  • block ser reuptake
  • neurogenesis in hippocampus (via BDNF)
  • 2 wks to work, kidney elim, block P450, high first-pass effect, binds plasma proteins
  • nausea, anxiety, insomnia… late: sex down
  • late: anorexia, mania
  • Antidepressant
51
Q

duloxetine

A

-SNRI’s
-block ser, NE reuptake (but UNRELATED to TCA’s)
-
-1/4 bound to plasma proteins, elim mostly kidney. metab by CYP1A2, CYP2D6
-nausea, anxiety, insomnia, sex down [same as SSRI’s!]
-high dose up blood pressure
-depression refractory to SSRI’s

52
Q

venlafaxine

A

-SNRI’s
-block ser, NE reuptake (but UNRELATED to TCA’s)
-
-mostly bound to plasma proteins, elim mostly kidney. metab by CYP2D6
-nausea, anxiety, insomnia, sex down [same as SSRI’s!]
-high dose up blood pressure
-depression refractory to SSRI’s

53
Q

bupropion

A

-atypicals

54
Q

mirtazapine

A

-atypicals

55
Q

nefazodone

A

-atypicals

56
Q

phenelzine

A

-MAOi’s

57
Q

selegiline

A

-MAOi’s

58
Q

tranylcypromine

A

-MAOi’s

59
Q

lithium

A

-bipolar treatment

60
Q

carbamazepine

A

-bipolar treatment

61
Q

olanzapine

A

-bipolar treatment

62
Q

risperidone

A

-bipolar treatment

63
Q

valproic acid

A

-bipolar treatment

64
Q

amphetamine

A

-Stimulants

65
Q

atomoxetine

A

-Stimulants

66
Q

dextro-amphetamine

A

-Stimulants

67
Q

methylphenidate

A

-Stimulants

68
Q

modafinil

A

-Stimulants

Backup 2 (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions