Pregnancy recognition Flashcards
When must embryonic motility occur post ovulation in the mare to recognize pregnancy?
11-16 days post ovulation
Ruminants have what mechanism to deliver PGF to the ovary?
Counter current exchange
What is required for maternal recognition in the cow?
Interferon-tao
What is prevented when the conceptus signals its presence?
luteolysis
What hormone destroys the CL?
prostaglandin
What hormone maintains pregnancy?
progesterone
What secretes prostaglandin?
Endometrium
What is the mechanism for luteolysis? What hormones are involved?
estrogen -> makes oxytocin receptors -> oxytocin binds -> prostaglandin produced
What does progesterone block the synthesis of?
Oxytocin receptors
What hormone promotes synthesis of OTR?
estrogen
Species with CL as sole source of progesterone
Dog, Cat, pig, goat, llama
Species with CL and placenta as source of progesterone
horse, sheep and cow
What is the normal lifespan of the CL?
15-17 days
What part of the female body is responsible for luteolysis?
uterus near ovary
How does PGF get to the ovary in counter current exchange in all species but the mare?
Endometrium -> uteroovarian vein -> ovarian artery -> ovary
How does luteolysis occur in the horse? How does PGF get to the ovary?
PGF travels systemically
How does the mare recognize pregnancy?
movement of the conceptus
How do the cow and sow recognize pregnancy?
expansion of conceptus
What does interferon tao prevent? In what species?
Lutyeolysis in ruminants
How does interferon tao work in ruminants?
prevents endometrium from making estrogen. Estrogen therefore cannot make OTR. Oxytocin therefore cannot bind and make PGF2a
How long is the luteal phase in a non-pregnant cat
30-45 days (shorter due to lack of CL)
ovulation still occurs without conception