Pregnancy Planning: Ovulation/ Pregnancy Testing + FSD Flashcards

1
Q

the ovum is viable for

A

12-24hrs

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2
Q

sperm can live up to

A

5 days

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3
Q

what are the 4 optimal times for fertilization

A

2 days before ovulation
day of ovulation
day after ovulation
(ideally 24hrs after LH surge)

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4
Q

how do saliva tests work for ovulation testing

A

as E increases, NaCl in mucus secretions increase = causes ferning of mucus when dried = large ferns = ovulating

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5
Q

saliva tests should provide _______ of advanced notification of ovulation

A

24-72hrs

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6
Q

how long must you sleep before getting a basal body temp

A

4hrs

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7
Q

what is the basal body temp

A

temp that occurs prior to rising in the morning

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8
Q

how do basal thermometers work for ovulation testing

A

Body temp rises as ovulation occurs- coincides with progesterone release
0.5F or 0.28C over 3 days (3 days of elevated temp = ovulation occurred)

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9
Q

what kind of mucus is usually seen in ovulation

A

thin/ clear

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10
Q

what are some issues with basal temp monitoring for ovulation

A

Ovulation may have occurred before actual detection
Interference: emotions, infections, movements, eating, drinking, talking, smoking

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11
Q

basal body temp measuring is best used in conjunction with

A

ovulation prediction tests

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12
Q

how often should you have sex once you have a + ovulation result
1. daily
2. BID
3. q2d
4. q3d

A

3

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13
Q

how do urine ovulation tests work

A

Use monoclonal antibodies specific to LH
LH gets sandwiched between 2 antibodies = color change
Color intensity dep amount of LH present

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14
Q

do 2 lines on an ovulation prediction tests always mean that you’re ovulating

A

no- may have low amount of LH it picks up
which is why it’s important to test 2-4 days before expected ovulation, then continue for 5-7 consecutive days to track the colour intensity

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15
Q

how should urine based ovulation tests be used

A

Begin testing 2-4 days before expected ovulation, then test for 5-7 consecutive days to determine color change

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16
Q

fertility monitors detects ______ and the rise of ________

A

LH and estrone-3-glucuronide (E3G)

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17
Q

fertility monitors can identify up to ____ fertile days and store ___ cycles of information

A

6 days
6 cycles

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18
Q

which of the following does not require regular cycles to easily use
1. saliva tests
2. ovulation urine tests
3. basal thermometers
4. fertility monitors

A

4

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19
Q

what are home sperm tests

A

self diagnostic tool, help decide if further clinical eval needed

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20
Q

what is a + result for home sperm tests

A

> 15-20million sperm/ mL

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21
Q

how do home sperm tests work?

A

Uses monoclonal antibodies that recognizes sperm specific acrosomal protein SP-10

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22
Q

when is the best time to use a home sperm test

A

at least 48hrs but no more than 7 days since last ejaculation

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23
Q

home sperm tests use antibodies that recognizes sperm acrosomal protein _____

A

SP-10

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24
Q

HCG in urine can be detected up to ____ after conception

A

6-8 d

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25
Q

after birth, HCG levels drop to undetectable after ____

A

8wks

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26
Q

HCG doubles ____ until peak at _____after conception, then ↓ to lower level throughout pregnancy

A

q2d
60-70d

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27
Q

at what time of day is HCG conc the highest

A

9am-12pm

28
Q

what is the most common reason for inaccurate pregnancy test results

A

human error

29
Q

urine HCG tests are sensitive to ____mIU/mL, blood ____mIU/mL

A

urine = 20
blood = 1

30
Q

what is a limitation of urine HCG tests

A

wide variations in HCG concentrations (12-2438mIU/mL) during 4th week of pregnancy

31
Q

if a pregnancy test is negative, when should you retest?

A

in 7 days if menses has not occured

32
Q

false + pregnancy tests may be due to

A

miscarriage or abortion in preceding 8wks, tumors which secrete HCG, fertility meds (ex- HCG injection)

33
Q

false - preg tests may be due to

A

test performed too early or too late, expired testing kit, chilled or dilute urine, cloudy/ pink/ red urine

34
Q

what is FDS

A

term used to collectively describe various conditions including low libido, sexual arousal, orgsmic dysfunction, and painful intercourse

35
Q

FDS is
1. underreported
2. includes painful intercourse and lack of orgasms
3. incudes sexual aversion disorder
4. all of the above

A

4

36
Q

what are the 4 types of FSD

A

desire
arousal
orgasmic
pain

37
Q

describe desire FSD

A

hypoactive sexual desire (low libido), sexual aversion disorder (disgust towards sex)

38
Q

what is arousal FSD

A

subjective arousal disorders ,genital arousal disorders, combined subjective and genital

39
Q

pain FSD includes

A

: dyspareunia (painful intercourse), vaginismus (vaginal spasms with penetration)

40
Q

list the 3 NT that have a + effect on desire and the one that has negative effect

A

+: testosterone, dopamine, estrogen
-: prolactin

41
Q

list the 4 NTs that have + and 1 that is - effect on arousal

A

+: NE, dopamine, ACh, NO
-: 5HT

42
Q

which NT has a + effect on orgasm? what about -?
1. serotonin
2. NE
3. dopamine
4. NO

A

NE +
serotonin -

43
Q

what is the PLISSIT model

A

permission
limited information
specific suggestions
intensive tx

44
Q

what RF modification may be done for FSD

A

smoking cessation, limit alcohol intake, treat alcohol/ illicit drug abuse, manage comorbidities (HPTN, DM, etc), switch to drugs with less sexual SEs

45
Q

what psychological tx may be done for FSD

A

CBT, sex tx, couples/ relationship tx, psychiatric counselling (ex- hx of sexual abuse), distraction techniques (fantasize, relaxation, etc)

46
Q

which of the following is not a treatment for FSD
1. vaginal dilators
2. vaginal estrogen therapy
3. transdermal testosterone therapy
4. mirtazapine

A

4

47
Q

testosterone therapy in women
1. is not approved by health canada for use in FSD
2. prefers PO testosterone
3. requires calculated dose out to 15mg/d
4. sees acne as the most common reason for d/c

A

1

48
Q

oral T for FSD in women can lead to

A

AEs on lipids (reduced HDL) and liver toxicity

49
Q

T dose for FSD is

A

5mg/d

50
Q

T or F: monitoring for T in FSD is recommended for efficacy at baseline ,then at 4-6wks

A

F- not for efficacy, for toxicity
monitoring levels may be insensitive and inaccurate

51
Q

free androgen index (FAI) =

A

total T/SHBG x 100

52
Q

what is the most common reason for T d/c in FSD
1. deepening of voice
2. acne
3. hair growth in application area
4. anger/ irritability

A

anger/ irritability

53
Q

testosterone FSD SEs

A

acne, hair growth (in application area), anger/ irritability (most common reason to d/c), deepening of voice (not common with small doses used for females)

54
Q

T or F: deepening of voice is uncommon in FSD with T use

A

T

55
Q

most PDE-5i studies in women have been with _____ for females with _____ induced dysfunction
it may also be useful for females with ________ to increase blood flow ot the area

A

with sildenafil
for females with SSRI induced dysfunction

spinal cord injury

56
Q

what are the 5 pharm tx for FSD

A

testosterone
PDE-5i
buproprion
DHEA
filbanserin

57
Q

buproprion is mainly used in __________ sexual dysfunction

A

SSRI induced

58
Q

DHEA in FSD has soem efficacy data in __________

A

adrenal insufficiency

59
Q

flibanserin is for

A

hypoactive sexual desire disorder in pre/ post menopausal women

60
Q

flibanserin MOA

A

5HT1A agonist + serotonin 2A antagonist

61
Q

flibanserin AEs

A

drowsiness, dizzy, fatigue, N, hyperthermia, limit EtOH (↑risk of syncope, hypotension, depression)

62
Q

how long should filbaserin be trialed

A

8wks

63
Q

filbaserin intx

A

mod/strong CYp3A4 inhibitors

64
Q

what are the 3 CAM products for FSD

A

L arginine
gingko bilbo
yohimbine

65
Q

L arginine is often topical for FSD and mixed with

A

menthol