Pregnancy & Lactation Information Flashcards

1
Q

Amiodarone

A

Congenital goiter/hypothyriodism and hyperthryroidism

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2
Q

Warfarin - Coumadin

A

Fetal hemorrhage and increased risk of spotaneous abortion

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3
Q

Phenytoin - Dilantin

A

Risk of cleft lips and cardiac defects in fetus

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4
Q

Phenobarbital

A

Crosses the placenta and may pose fetal harm
Use in last trimester may cause withdrawal symptoms in infants. Excreted into human breast milk; monitor infant for sedation

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5
Q

Lithium

A

May cauase fetal harm
Excreted into human breast milk - avoid use during breastfeeding

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6
Q

Clozapine

A

Other agents preferred in pregnancy
Health care providers are encouraged to enroll women 18 to 45 years of age exposed to clozapine during pregnancy in the Atypical Antipsychotics Pregnancy Registry

Not recommended for breastfeeding women due to side effects

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7
Q

Isotretinoin

A

Boxed warning for teratogenicity

Breastfeeding not recommended during treatment and for 1 month after last dose due to potential for serious adverse effects

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8
Q

Phentermine/topiramate

A

Increased risk of congenital malformations, specifically orofacial clefts, in infants exposed during 1st trimester

Not recommended for breastfeeding women due to side effects

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9
Q

Valproic acid

A

Boxed warning for causing congenital malformations, particularly neural tube defects (spina bifida)

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10
Q

Carbamazepine

A

Teratogenic effects, higher risk with higher doses and anticonvulsant polytherapy than monotherapy

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11
Q

Oxycodone + Acetaminophen

A

Boxed warning for neonatal opioid withdrawal syndrome if used during pregnancy

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12
Q

Codeine + Acetaminophen - Tylenol #2, Tylenol #3

A

Boxed warning for neonatal opioid withdrawal syndrome if used during pregnancy

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13
Q

Hydrocodone + Acetaminophen - Vicodin

A

Boxed warning for neonatal opioid withdrawal syndrome if used during pregnancy

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14
Q

Fentanyl - Duragesic

A

Boxed warning for neonatal opioid withdrawal syndrome if used during pregnancy

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15
Q

Oxycodone - OxyContin

A

Boxed warning for neonatal opioid withdrawal syndrome if used during pregnancy

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16
Q

Methadone - Dolophine

A

Boxed warning for neonatal opioid withdrawal syndrome if methadone is used during pregnancy

17
Q

Buprenorphine

A

Boxed warning for neonatal opioid withdrawal syndrome if used during pregnancy

18
Q

Buprenorphine/naloxone - Suboxone

A

Limited safety data with buprenorphine/naloxone combination so treatment with combination product should not be initiated in pregnancy