Pregnancy Flashcards
Cyclosporine TERIS category?
small-moderate
FDA class C
Lamotrigine TERIS category?
minimal-small
FDA class C
nifedipine TERIS category?
non-minimal
FDA class C
New labeling rule makes it difficult to make blanket formulary decisions b/c each med will need a more individualized review.
a. true
b. false
a. true
requires review of available evidence instead of relying on category designations
___ cause alteration of tissue development or organ formation
a. teratogenic effects
b. adverse fetal effects
a. teratogenic effects
occur in 1st trimester
neural tube defects, congenital heart abnormalities, cleft lip/palate, fetal stillbirth
___ results in dysfunction of an organ or tissue after that organ/tissue has been formed
a. teratogenic effects
b. adverse fetal effects
b. adverse fetal effects
difficult postnatal adaptation, withdrawal, electrolyte abnormalities, altered glucose metabolism
2 transport mechanisms of placenta?
passive diffusion (majority) P-gp pumps
Tocolytic therapy is generally not utilized beyond __ weeks of gestation
34
prolongs pregnancy:
- terbutaline
- mag sulfate
- nifedipine
- indomethacin
4 tocolytic drugs?
terbutaline
mag sulfate
nifedipine
indomethacin
prolong pregnancy between 48 hours to 1 week
What is the purpose of antenatal corticosteroids?
fetal lung maturation
betamethasone or dexamethasone IM
If woman is in labor and no GBS screening info available antibiotics given for fever > __C
38
100.4
If woman is in labor and no GBS screening info available antibiotics given for membrane rupture at least __ hours prior
18
If woman is in labor and no GBS screening info available antibiotics given for gestation under __ weeks
37
What is drug of choice for GBS?
pen G or ampicillin
What antibiotic is given for GBS in women with penicillin allergy but no risk for anaphylaxis ?
cefazolin
