Infectious Disease

Question 1

extremely preterm is born before __ weeks

Answer 1

28

Question 2

very preterm is born between __ to __ weeks

Answer 2

28, 32

Question 3

moderate to later preterm is born between __ to __ weeks

Answer 3

32, 37

Question 4

CRP > __ mg/dL is diagnostic for neonatal infection

Answer 4

1

platelet count < 100,000
immature to total neutrophil ratio > 0.2

Question 5

TORCH congenital infections:

Answer 5

T - toxoplasmosis
O - other (chickenpox, chlamydia, HIV, syphilis)
R - rubella
C - cytomegalovirus
H - herpes simplex virus

Question 6

2 main bacteria for early onset sepsis?

Answer 6

Group B strep (S. agalactiae)

E. coli

Question 7

First line empiric Tx for early onset sepsis?

Answer 7

amp + gent

Question 8

Early onset sepsis Tx for confirmed E. coli?

Answer 8

amp monotherapy or cephalosporin

Question 9

Early onset sepsis Tx for confirmed enterococcus?

Answer 9

ampicillin or vanc

Question 10

Early onset sepsis rule out Tx duration?

Answer 10

48 hours

Question 11

Early onset sepsis presumed sepsis Tx duration?

Answer 11

7-10 days

Question 12

Early onset sepsis confirmed sepsis Tx duration?

Answer 12

10 days

Question 13

Early onset sepsis GBS meningitis Tx duration?

Answer 13

14 days

Question 14

Early onset sepsis listeria or GNR meningitis Tx duration?

Answer 14

21 days

Question 15

What cephalosporin is contraindicated in neonates due to risk of kernicterus?

Answer 15

ceftriaxone

Question 16

Gentamicin MOA?

Answer 16

inhibits 30s ribosomal subunit

Question 17

Early onset sepsis does not have horizontal transmission

a. true
b. false

Answer 17

a. true

vertical
perinatally acquired

Question 18

Main bacteria for late onset sepsis?

Answer 18

CoNS

Question 19

late onset sepsis presumed sepsis Tx duration?

Answer 19

7-10 days

Question 20

confirmed sepsis confirmed sepsis Tx duration?

Answer 20

10-14 days

Question 21

CoNS or S. aureus late sepsis Tx duration?

Answer 21

14 days

Question 22

late onset sepsis candida Tx duration?

Answer 22

21 days