Pregnancy Flashcards
What is the change in resting heart rate in pregnancy? What causes it?
Up 25% (5-10 in first trimester and 15 in 2/3)
Due to increase in oestrogen and hCG
SNS as well to stop BP dropping
What is the change in stroke volume in pregnancy and why?
Increase 25%
Progesterone increases renin and therefore reabsorption and therefore blood volume
LV and contractility increases due to oestrogen and having more blood
10% in first trimester
What is the change in plasma volume in pregnancy?
Up 35-50%
What is the effect of pregnancy on BP and what blood related conditions may occur?
BP stays constant due to increased venous capacity negating increased CO
Potential anaemia as RBC do not increase as much as plasma
Risk of clots and varicose veins
What are the pulmonary changes?
Elevation of diaphragm due to uterus reducing reserve volume
Ribs flair outwards reducing effectiveness
Increased work of breathing due to diaphragm resistance
Resting hyperventilation due to progesterone increasing CO2 sensitivity
What is the effect of pregnancy on endurance athletes?
Initial improvement of performance for the first 15 weeks before weight and size start effecting as there is more blood
Then decrease due to foetal O2 demand and body mass
What is the effect of pregnancy on substrate usage?
Increased CHO usage and maternal insulin (oestrogen stimulates beta cells)
May cause hypoglycaemia
Mum burns more of own body fat due to foetus needing glucose
Explain gestational diabetes
Human placental lactogen counters insulin and insulin resistance is developed. More common in obese mothers and 60% go on to T2D
May cause large babies
What is pre eclampsia and what is the effect of exercise?
High BP in pregnancy (3-7% prevalence)
Active women have 35-70% less preeclampsia possibly due to less CRP (vasodilation via more NO) and Leptin (less SNS)
What are the GI changes in pregnancy?
Progesterone and larger uterus causes: constipation, less motility and relaxation of Lower oesophageal sphincter and therefore reflux
What are the musculoskeletal changes of pregnancy?
Enlarged uterus and breasts affects centre of gravity, can cause back/shoulder pain and exaggerates lumbar lordosis
Lax joints and ligaments
Separation of abdominal muscles due to enlarging uterus 20-90% incidence
Overall what is the changes in body mass and due to what?
12kg weight gain Foetus 3.5 Uterus 1 Placenta 0.6 Amniotic fluid 0.8 Breasts 1.5 Maternal fluid 2 Maternal fat 2.5
What is the acute effect of exercise on the foetus?
May cause less blood to uterus but the foetus can extract more
Foetal tachycardia due to heat and Catecholamines
Foetal bradycardia if hypoxia to reduce demands
If mum becomes hyperthermic would be bad as less heat gradient for baby to lose heat. Doesn’t seem to happen though
What is the chronic effect of exercise on the foetus?
Inconsistent evidence about birth weight but seems fine if positive energy balance maintained. Too much in late pregnancy may make baby thinner
I theory shorter gestation but no evidence
What are some contraindications for exercise in pregnancy?
Heart disease, restrictive lung, incompetent cervix, risk of premature labour
Relative - severe anaemia, dysthymia, bronchitis, T1DM
During - very out of breath, chest pain, dizzy, contractions