Pregnancy Flashcards
___ increases by 40% in pregnancy, with most of the increase due to an increase in stroke volume.
Cardiac output
Heart rate increases by ~10 beats/min during the ____
third trimester.
The diagnosis of hypertension requires the measurement of ___ elevated blood pressures at least ___ apart.
two
4 h
Preeclampsia criteria
Criteria (onset after 20 weeks of gestation):
Hypertension (blood pressure ≥140/90 mmHg).
Proteinuria:
24-h urinary protein >300 mg/24 h.
Protein-creatinine ratio ≥0.3.
Can be diagnosed without proteinuria if symptoms or lab abnormalities suggest end-organ damage.
HELLP syndrome
hemolysis, elevated liver enzymes, low platelets)
Specific clinical features qualify as evidence of severe disease, including severe hypertension (blood pressure ___), new-onset symptoms (headache not responsive to medications, visual changes, unremitting severe epigastric pain, or pulmonary edema), or laboratory abnormalities signifying thrombocytopenia (platelets <100 × 109 /L), renal insufficiency (creatinine >1.1 mg/dL), or liver impairment (elevation of transaminases to twice the normal concentration).
≥160/110 mmHg
The development of elevated blood pressure after 20 weeks of pregnancy in the absence of preexisting chronic hypertension or proteinuria is referred to as ____
gestational hypertension
____initiated between ____ weeks of gestation reduces the risk in women at high risk of developing preeclampsia.
Low-dose aspirin
12 and 14
This is the preferred agent to prevent eclampsia in patients with preeclampsia with severe features and for treatment and prevention of recurrent seizures in patients with eclampsia.
Magnesium sulfate
The first-line agents to manage severe h sion in preeclampsia with consideration of oral agents once blood pressure is controlled.
Labetalol, hydralazine
In preeclampsia without severe features, delivery at ____ is recommended.
37 weeks
For women with preeclampsia with severe features, delivery is recommended unless the patient is ____ weeks and eligible for expectant management in a tertiary hospital setting.
<34 weeks