Prefrontal cortex and executive functions Flashcards

Teacher: Tonny

1
Q

Efficient goal-directed behavior - Match the task with what’s to be researched:

  1. Memorize the proper goals, subgoals and the order of subgoals
  2. Select the proper perceptual input and prioritize the selection
  3. Inhibition of irrelevant perceptual input & inhibit motor actions
  4. Activate the proper motor actions
  5. Evaluate your actions. Did they match your expectations
  6. Adjust (sub)goals and the order of your actions if necessary

Inhibition - Evaluative control - Attention - Working memory - Executive control - Motor action

A
  1. Working memory
  2. Attention
  3. Inhibition
  4. Motor action
  5. Evaluative control
  6. Executive control
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2
Q

Match goal-directed behavoir with the right brain area:
1. Working memory
2. Attention
3. Inhibition
4. Motor
5. Evaluation
6. Executive control

Areas:
Frontal eye field, basal ganglia (BG), Anterior cingulate cortex (ACC), M1, Dorsolateral PFc(dlPFc), supplementary motor area(SMA), superior parietal lobe(SPL), inferior frontal gyrus(IFG), Pre-SMA

A
  1. dlPFC, SPL
  2. Frontal eye field, SPL
  3. Pre-SMA, IFG
  4. SMA, M1, BG
  5. ACC
  6. ACC to dlPFc
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3
Q

What is the definition of the prefrontal cortex?

A

Gets input from medio dorsal thalamus

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4
Q

Which part of the thalamus plays a role in behavioral & emotional states?

A

Paraventricular thalamus (to PFc)

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5
Q

Which pathway does not primarily anterograde with prefrontal cortex?

A

Medio Dorsal Thalamus to Accumbens

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6
Q

What problem can damage to the ventral/medial PFc cause?

A

Disinhibition syndrome

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7
Q

What problem can damage to the lateral PFc cause?

A

Dysexecutive syndrome

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8
Q

What is disinhibition syndrome?

A

Person can not inhibit in a social/non-social sense (e.g. screaming), constant movement, NO dysexecutive symptoms

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9
Q

What is dysexecutive syndrome?

A

Person has problems with planning and organization, working memory, confabulate, limited attention span, difficulties coping real world

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10
Q

What are common features when there is damage to the frontal lobe?

A

No deficit in intelligence, normal language use, normal memory for events and facts
- Problems: impairment in forming/updating and implementing of rules appropriate/effective behavior

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11
Q

Match frontal area with their function:
1. The conscious choice in attention and thought
2. Inhibition of behavior: The choice NOT to do something
3. Emotional and social control
4. Behavioral evaluation: What did I do and is that what I anticipated

Anterior Cingulate Cortex, Dorso-lateral PFc, Orbito frontal PFc, Ventro medial PFc

A
  1. dlPFc
  2. Orbito frontal PFc
  3. Ventro-medial PFc (disinhibition syndrome)
  4. ACC
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12
Q

In with prefrontal brain areas does motivation come from?

A

Ventro-medial PFc and Orbito-frontal PFc

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13
Q

In with prefrontal brain areas does action result come from?

A

ACC and dorso-lateral PFc

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14
Q

What are the 3 types of executive functions?

A

Establishing and modifying rules
Contextual control
Working memory

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15
Q

What is the difference in stimulus-response learning and abstract learning?

A

S-R learning: Learn an appropriate action for each and every stimulus (or combo)
Abstract learning: Learn rules that connect stimuli to actions

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16
Q

What brain areas are involved in executive functions and which for all exert behavior?

A

Executive functions: dlPFc, VMPFc, VLPFc
Exert behavior: via basal ganglia

17
Q

What is the function of the lateral PFc in inhibiting processes?

A
  • Halting behaviors that are well trained or previously valid
  • Preventing irrelevant information from interfereing
  • Restraining actions that are inappropriate in social contexts
  • Removing irrelevant information from working memory
18
Q

Which area is involved in the Oddball paradigm?

A

dlPFc

19
Q

What is the function of the Vlateral PFc in inhibiting processes?

A
  • Important for filtering out task irrelevant information
20
Q

Where is initiating new rules and shifting among rules processed?

A

Lateral PFc