Predicting Solubility Flashcards
1
Q
Very water soluble drugs have difficulty…
A
crossing membranes
2
Q
Very water soluble drugs will have ___ bioavailability if oral
A
low
3
Q
Which kinds of molecules can cross into membranes or BBB?
A
uncharged only
4
Q
Why do highly lipophilic drugs cause interactions?
A
- high protein binding
- stomach problems if taken orally (should take with fatty meals)
