Precocious Puberty

Question 1

what is precocious puberty?

Answer 1

development of secondary sexual characteristics before 8 years in females and 9 years in males

Question 2

what gender is more at risk of precocious puberty?

Answer 2

females

Question 3

what is thelarche?

Answer 3

first stage of breast development

Question 4

what is adrenarche?

Answer 4

first stage of pubic hair development

Question 5

what are the 2 classifications of precocious puberty?

Answer 5

1. gonaotrophin dependent (‘central’, ‘true’)
2. gonadotrophin independent (‘pseudo’, ‘false’)

Question 6

what is gonadotrophin dependent precocious puberty caused by?

Answer 6

premature activation of the hypothalamic-pituitary-gonadal axis

Question 7

early puberty + raised FSH and LH

Answer 7

gonadotrophin dependent precocious puberty

Question 8

early puberty + low FSH and LH

Answer 8

gonadotrophin independent precocious puberty

Question 9

what

Question 10

what is gonadotrophin independent precocious puberty caused by?

Answer 10

excess sex hormones

Question 11

early puberty + bilateral testes enlargement

Answer 11

gonadotrophin release from intracranial lesion

Question 12

early puberty + unilateral testes enlargement

Answer 12

gonadal tumour

Question 13

early puberty + small testes

Answer 13

adrenal cause (tumour or adrenal hyperplasia)