Precocious puberty Flashcards
1
Q
Central causes precocious puberty
A
CNS
Idiopathic
Hypothyroidism
2
Q
Peripheral causes precocious puberty
A
Adrenal (tumour, CAH)
Ovarian (tumour)
McCune Albright syndrome
Medications
3
Q
Investigations for precocious puberty
A
hcg swabs FSH, LH, oestrodiol TSH, Prolactin Virilisation: testosterone, DHEA, androstenedione, 17-OH progesterone (consider synacthen ACTH test) Karyotype Pelvic USS MRI head adrenal scan Bone age X ray
4
Q
Adolescent gynae examination
A
BMI - growth chart velocity general appearance, stigmata of turners skin - cafe au lait, acanthrosis nigricans, violaceous striae virilisation tanner staging - pubic hair, breast development Neuro-visual fields abdo genital exam
5
Q
Management precocious puberty
A
MRI head MDT - paediatric endocrinologist Consider GnRH agonists Counselling 3/12 R/V yearly bone age xray
