Prebiotics, probiotics and human microbiome in health Flashcards
1
Q
How many microbes are there?
A
over 100 trillion
2
Q
What are the features of the microbes?
A
- distinct spatial organisation
- site-dependent composition
- marked inter-individual variation
- highly conserved functinality
3
Q
What are the sites of human microbiome?
A
- skin
- oral
- digestive tract
- urogenital tract
4
Q
What types of microbes are there?
A
- viruses
- bacteria
- parasites
- fungi
5
Q
What are the immunological functions of microbiome?
A
- maintenance of tolerance
- competitive inhibition of pathobionts
6
Q
What are the metabolic functions of the microbiome?
A
- fermentation (SCFAs)
- metabolism of bile acids, sterols
- micronutrient synthesis (thiamine, folate, vit. K)
7
Q
What is dysbiosis:
A
perturbation in composition, function or organisation of microbiota
