Pradaxa Flashcards

1
Q

What is PRADAXA?

A

PRADAXA is a direct anti-IIa anticoagulant.

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2
Q

What is the dosage of PRADAXA for hip/knee surgical prevention?

A

110 mg twice daily in one dose.

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3
Q

What is the dosage of PRADAXA for atrial fibrillation (FA)?

A

150 mg twice daily.

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4
Q

What percentage of PRADAXA is eliminated renally?

A

80%.

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5
Q

What is the half-life of PRADAXA?

A

12-17 hours.

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6
Q

What are the contraindications for PRADAXA?

A

Contraindicated if DFG < 30.

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7
Q

What is the recommendation for low hemorrhagic risk?

A

No dose the night before and morning of the procedure; resume 6 hours after the procedure.

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8
Q

What is the recommendation for high hemorrhagic risk?

A

Last dose at J-4 if DFG > 50; and J-5 if DFG = 30-49.

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9
Q

What is the antidote for PRADAXA?

A

Idarucizumab (PRAXBIND).

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