practice quiz 7 Flashcards

1
Q
In which of the following organelles would you expect to first find a protein destined to be secreted from a cell?
A) endosome
B) Golgi apparatus
C) lysosome
D) secretory vesicle
E) endoplasmic reticulum
A

E

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2
Q

The endoplasmic reticulum is a site for
A) potassium storage in muscle cells.
B) drug detoxification by catalase.
C)C N-linked glycosylation of polypeptides.
D) addition of lipid residues.
E) degradation of foreign material brought into the cell by phagocytosis.

A

C

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3
Q

Comparing cells synthesizing secretory proteins and cells secreting steroid hormones, the cells synthesizing the steroid hormones have
A) more rough ER.
B) more smooth ER.
C) equal amounts of smooth and rough ER.
D) equal amounts of smooth and rough ER, but more lysosomes.
E) equal amounts of smooth and rough ER, but fewer lysosomes.

A

B

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4
Q
Which of the following molecules forms the coat during receptor-mediated endocytosis-coated pit formation?
A) mannose-6-phosphate B) T-SNARE
C) clathrin
D) tethering protein
E) caveolin
A

C

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5
Q

. The continuous release of mucus by the epithelial cells lining the respiratory tract is an example of
A) regulated secretion.
B) constitutive secretion.
C) the mucus response.
D) clathrin-coated pit formation. E) phagocytosis.

A

B

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6
Q

The vesicles that are anchored to the plasma membrane at a nerve cell presynaptic site are specialized for
A) constitutive secretion. B) regulated secretion. C) polarized secretion. D) lysosome secretion. E) endocytosis.

A

C

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7
Q

Which of the following statements is false regarding phagocytosis?
A) It can ingest large particles.
B) It involves the projection of pseudopods.
C) It is used by amoebae to ingest food.
D) It is mediated by clathrin at the plasma membrane.
E) It is used by macrophages and neutrophils to ingest bacteria.

A

D

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8
Q

In receptor-mediated endocytosis, each of the following is a fate for the receptors and/or
vesicle contents except
A) transcytosis.
B) digestion in a lysosome.
C) recycling to the plasma membrane.
D) release from the vesicle into the nucleus.
E) All are possible fates.

A

D

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9
Q

Peroxisomes
A) are not derived from the endoplasmic reticulum.
B) are bounded by double membranes.
C) possess acid phosphatase activity.
D) possess mannose phosphotransferase activity.
E) exist only in algae and photosynthetic cells in plants.

A

A

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10
Q
Which of the following organelles has the ability to catabolize alkanes found in oil and petroleum products?
A) mitochondria
B) smooth endoplasmic reticulum
C) peroxisomes
D) lysosomes
E) late endosomes
A

C

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11
Q

A protein that is N-glycosylated is expected to be A) secreted from the cell.
B) retained in the endoplasmic reticulum. C) localized in the Golgi body.
D) imported into a cell by endocytosis.
E) a peroxisome enzyme.

A

A

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12
Q

Each of the following is an endoplasmic reticulum function except
A) addition of carbohydrate to proteins to make glycoproteins.
B) peptide folding.
C) the assembly of multimeric proteins.
D) the export of protein that cannot be folded into the cytoplasm for destruction.
E) All are endoplasmic reticulum functions.

A

E

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13
Q
Each of the following organelles is part of the endomembrane system except
A) the peroxisome.
B) the Golgi complex.
C) the smooth endoplasmic reticulum.
D) the endosome.
E) the rough endoplasmic reticulum.
A

A

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14
Q

Each of the following is true about botulinum toxin (Botox) except
A) The toxin is one of the most potent toxins known.
B) Botox is a SNARE protein.
C) It can be used therapeutically to stop muscle spasms.
D) It has been used to remove wrinkles caused by muscle contractions.
E) It has potential use as a migraine headache treatment.

A

B

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15
Q
Each of the following is a component involved in the SNARE hypothesis model mechanism except
A) v-SNARE.
B) Rab GTPase.
C) tethering complex.
D) NSF protein.
E) All are involved.
A

E

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16
Q
Pancreatic acinar cells produce and store hydrolytic enzymes in zymogen granules until hormones signal the cell to release the enzymes in a process known as
A) transport secretion.
B) regulated secretion.
C) constitutive secretion.
D) intracellular secretion.
E) consistent secretion.
A

B

17
Q
Which of the following proteins requires GTP in the process of LDL receptor-mediated endocytosis?
A) LDL receptor 
B) dynamin
C) AP-2 complex
D) uncoating enzyme E) clathrin
A

B

18
Q

A protein that is normally localized in the cytoplasm has been engineered so that it will be secreted from the cell instead. Which of the following represents the most likely pathway for the protein after it has been completely synthesized?
A) rER → Golgi → secretory vesicle → environment
B) rER → Golgi → sER → cytoplasm → environment
C) cytoplasm → rER → Golgi → secretory vesicle → environment
D) sER → Golgi → secretory vesicle → environment
E) rER → secretory vesicle → Golgi → environment

A

A

19
Q
In animal cells, oxidation of very long fatty acids occurs in
A) mitochondria.
B) peroxisomes.
C) lysosomes.
D) the smooth endoplasmic reticulum.
E) residual bodies.
A

B

20
Q
Which of the following cell types would be associated with the greatest concentration of low-density lipoproteins (LDLs)?
A) skin
B) muscle
C) connective tissue D) blood
E) liver
A

E

21
Q

Uptake of low-density lipoproteins (LDLs) occurs by
A) simple diffusion.
B) phagocytosis.
C) facilitated transport.
D) receptor-mediated endocytosis. E) pinocytosis.

A

D

22
Q
The low pH of lysosomes is established by
A) acid hydrolases.
B) ATP-dependent proton pumps.
C) β-glucuronidases.
D) catalases.
E) superoxide dismutases.
A

B

23
Q
Which of the following cellular processes may be inhibited in tumor cells? 
A) autophagy
B) N-linked glycosylation 
C) caveolae uptake
D) LDL degradation
E) catalase activity
A

A