Practice Exam Flashcards

1
Q

T/F

Renal excretion rate for solute can never exceed filtered load

A

False

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2
Q

What hormone produced by kidney in response to SNS +

A

Renin

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3
Q

What would increase GFR but decrease renal blood flow

A

Constriction of efferent arterioles

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4
Q

What can kidney produce fro alanine, glycerol, lactate

A

Glucose

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5
Q

What hormone produced by kidneys stimulates production of RBC

A

EPO

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6
Q

What percentage of resting CO does kidneys receive

A

25%

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7
Q

At rest glomerular filtration rate averages what quantity of plasma filtrate

A

125 ml/min

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8
Q

Average urine production in day is equal to which of following

A

1500 ml/day

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9
Q

Why does capillary hydrostatic P stay constant along length of glomerular capillary

A

Due to high resistance efferent arterioles

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10
Q

In kidney, where does reabsorption take place

A

Peritubular capillaries

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11
Q

Majority of nephrons are capable of concentrating urine

T/f

A

False

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12
Q

Process of micturition, what sphincter is under voluntary control allowing us to decide when to urinate

A

External urethral sphincter

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13
Q

What causes contraction of detrusor muscle and relaxation of internal sphincter, giving urge to urinate

A

+ of PSNS

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14
Q

On average what percent of body weight is total body water

A

60%

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15
Q

On average what % of body weight is ECF

A

20%

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16
Q

If you dehydrate and lose 2 L fluid, what kind of fluid shift would you expect

A

Some fluid would shift from ICF to ECF

17
Q

Which marker best suited to measure total body water

A

Isotropic water

18
Q

What fluid loss would cause only loss in ECF volume, no change in osmolarity and no shift in volume between ICF and ECF

A

Diarrhea

19
Q

Clearance of what injected substance equal to glomerular filtration rate

A

Inulin

20
Q

What substance has high clearance rate

A

PAH

21
Q

At normal blood levels, how can renal handling of glucose be described

A

Freely filtered, all reabsorbed

22
Q

Physiologic significance of substance x with clearance ratio = 1

A

Clearance of X equal to GFR

23
Q

Most important function of kidney

A

Reabsorption of Na

24
Q

What % of Na is reabsorbed in proximal tubule

A

66%

25
Q

When would some filtered glucose first spill into urine

A

Plasma concentration of glucose first exceeds 200 mg/dL

26
Q

Physiologic Function of urea in kidneys

A

Helps create osmotic gradient important in concentration of urine

27
Q

What located on basolateral side of tubular cell that drives reabsorption of most solutes in PT

A

Na K ATPase

28
Q

Thick AL has what effect on tubular fluid

A

Dilutes it

29
Q

What tubular cell in late DT responsible for K secretion

A

Principal cell

30
Q

What effect does insulin have in intracellular K concentration

A

Increase

31
Q

What receptors mediate ADH effect to insert aquaporin 2 (makes CD permeable to water which allows reabsorption of water)

A

V2

32
Q

Normal arterial pH

A

7.4

33
Q

Hyperventilation cause of

A

Respiratory alkalosis

34
Q

Normal compensation to metabolic acidosis

A

Increased ventilation

35
Q

If renal perfusion pressure increases by 50 mmHg what is true

A

Both GFR and renal blood flow would stay constant

36
Q

Most autoregulation of renal blood flow and GFR involves constriction or dilation of what vessels

A

Afferent arterioles

37
Q

Clearance of PAH equal to

A

Renal plasma flow

38
Q

What condition does renal excretion of acid increase 10 fold

A

Diabetic ketoacidosis