Practical question 2 Flashcards
1
Q
Single i.v log graph
A
X axis = time
Y axis = ln[C]
Gradient = -ke
Y intercept = Ln[C0]
2
Q
Half life
for single iv
A
t0.5 = 0.693/ke
3
Q
Working out clearance
single iv
A
AUC = C0/ke
Clearance = dose/AUC
4
Q
Volume of distribution
single iv
A
Vd = clearance/Ke
5
Q
Assumptions for single iv injection single compartment
A
Well mixed so no distribution
1st order elimination
Drug equally distributed at same conc as plasma
