praccy exam 3 Flashcards
a mutation in the Ca2+ binding region of calmodulin will most likely result in ____
myosin cannot interact with actin
Fish-hunting snails inject toxins into their victims that block acetylcholine receptors at the neuromuscular junction and cause muscle paralysis. The toxin is most likely binding to ___
ligand-gated Na+ channels
Ca2+ binding to the TnC subunit permits the transition of thin filament from the ____
blocked to closed state
In skeletal and cardiac muscles, Ca2+ is stored in the _____
sarcoplasmic reticulum
Fine-tuning force generation by triggering action potentials before the muscle can fully relax is an example of _____
twitch summation
muscles with predominately ____ fibers are more resistant to lactic acid buildup
slow
Isometric contraction occurs when there is ____
no change in muscle length
Cardiac output can be increased by ____
-increased venous return
-increased heart rate
-increased stroke volume
-increased end-diastolic volume
the greatest diameter and lowest pressure in a blood vessel would be found in the ____
vena cava
Frank-starling mechanism where muscle length determines force generation. Physiologically the cardiac muscle present in the _____ of the force-length relationship
ascending limb
ventricular filling is complete immediately after the
p wave
which of the following blood vessels carries oxygenated blood back to the heart
pulmonary veins
The threshold for rapid depolarization in autorhythmic cardiac cells is reached by the activity of the ____
hyperpolarization cyclic nucleotide (HCN) gated Na+ channels
the autonomic nervous system can ____ heart rate by causing ____ of the membrane potential of pacemaker cells
decrease, greater hyperpolarization
in the pressure-volume loop, the end-diastolic volume is most directly indicative of _____
preload