Posterior pituitary Flashcards

1
Q

what 2 hormones are secreted from the posterior pituitary and their function

A

ADH - controlling water secretion in urine
Oxytocin - expression of milk, promotes starting labour

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2
Q

define osmolality

A

Concentration of particles per kilo of fluid

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3
Q

Body water loss = ______ in osmolarity

a)increase
b)decrease

A

increase

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4
Q

increased osmolarity = _______ in ADH

a)increase
b) decrease

A

increase

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5
Q

Is ADH and oxytocin produced in hypothalamus or posterior pituitary

A

Produced in hypothalamus and is secreted by the posterior pituitary

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6
Q

total body water = xLitres

A

42

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7
Q

When drinking water what happens to the following

Plasma osmolality
Thirst
Water intake
ADH
Renal water excretion
Total body water

A

decrease
decrease
decrease
decrease
increase
decrease

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8
Q

when in water deficit what happens to the following

Plasma osmolality
Thirst
Water intake
ADH
Renal water excretion
Total body water

A

increase
increase
increase
increase
decrease
increase

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9
Q

what stimulates production of aquaporins in the collecting ducts

A

ADH

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10
Q

which 2 types of receptors regulate ADH release

A

osmoreceptors in the hypothalamus

Baroreceptors within arterial system detect blood pressure inc/dec

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11
Q

which substances affect osmolality

A

sodium, potassium, chloride, bicarbonate, urease and glucose

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12
Q

what is a normal osmolality

A

282-295 mOsmol/Kg

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13
Q

what can affect vasopressin

A

age, pregnancy, rapid water intake

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14
Q

If a patient is passing 6 litres per day with a sodium of 154 mmcl/l,

What is the relevant physiology
What is the relevant anatomy
what is differential diagnosis

A

ADH its not being secreted
Poster pituitary/kidney damage
polyuria, habitual drinkers

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15
Q

polyuria =

A

large volume urine

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16
Q

Polydypsia=

A

Small quantity of urine

17
Q

which nucleus oxytocin produces in

A

paraventricular nucleus in hypothalamus

18
Q

which nucleus is ADH produced in

A

supraoptic nucleus in hypothalamus

19
Q

what is the name of the receptor thatt ADH bind to in the collecting duct to produce aquaporin2

A

V2