Anterior pituitary Flashcards
List the anterior pituitary hormones
Thyroid stimulating hormone (TSH)
Follicle stimulating hormone (FSH)
Luteinising hormone (LH)
Adrenocorticotrophic hormone (ACTH)
Growth Hormone (GH)
Prolactin
discuss thyroid stimulating hormone
-type of hormone
-functon
peptide
Increased metabolism, increased sympathetic action, heat production, essential for growth and development too.
Does anterior pituitary have its own blood supply
no but received blood from portal venous system
Discuss prolactin
-type of hormone
-function
Peptide
produced in lactotrophs and stimulates lactation and helps with breast development
Discuss leutenizing hormone (LH)
-function
-type of hormone
controlling gonads
-peptide hormone
Describe growth hormone (GH)
-type of hormone
-function
peptide
-produced in somatotrophs and stimulates growth and protein synthesis
Describe follicular stimulating (FSH)
-type of hormone
-function
peptide
-produced in gonadotrophs and target gonads, stimulates germ cell development, stimulates release of hormones
Describe Adrenocorticotrophic hormone (ACTH)
-type of hormone
-function
-peptide
-Glucocorticoid + adrenal androgen production
which is the only anterior pituitary hormone that doesnt have negative feedback
prolactin
Describe pituitary development
-Anterior and posterior glands develop from different tissues before joining together
-Protrusion of ectoderm from Rathke’s pouch grows upwards to form anterior pituitary (adenohypophysis)
-Posterior pituitary is neuronal (neurohypophysis) and is extension of neural components of hypothalamus
-2 tissues grow tightly apposed despite being different origins
What can pituitary tumours cause?
-Pressure on local structures e.g. optic chiasm. Can result in bitemporal hemianopia
-Pressure on normal pituitary function; hypopituitary.
-Functioning tumour can result in Cushing’s disease, gigantism and prolactinoma.
