Poster 11: Reptile Salmonellosis Flashcards
1
Q
background
A
- commensal for reptiles
- normally asymptomatic
- clinical severity increases with high stocking density, contaminated diets, deficient hygiene and stress
2
Q
Mechanism of disease
A
- salmonella induces host cell to engulf using type 3 injector system
- injected proteins trigger epithelial cell membrane to ruffle
- bacterium encased in vacuole made of host membrane
- injects other bacterial proteins into surrounding vacuole. altering vacuole structure and blocking fusion with lysosomes
- bacteria continue to divide while vacuole grows and bacteria thought to escape when proliferation exceeds vacuole capacity
3
Q
Transmission
A
- majority of salmonellosis comes from cecal-oral transmission
- shed through skin or cloaca
- turtles <4 inches high risk because toddlers more likely to put them in mouth
4
Q
Clinical signs
A
- gastroenteritis
- colitis
- blood infections
- meningitis
5
Q
treatment
A
- antibiotics not recommended as reptiles often reinfect themselves
- promotes AMR
- may be detrimental to animals that have it as commensal bacteria